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Glp 1 Drugs

All articles tagged with #glp 1 drugs

GLP-1 Weight Loss Linked to Lower Obesity-Related Disease Risk in Large Real-World Study
health12 hours ago

GLP-1 Weight Loss Linked to Lower Obesity-Related Disease Risk in Large Real-World Study

A real-world study of 89,718 US patients starting GLP-1 or GLP-1/GIP drugs found that greater weight loss during the first year (BMI drop ≥15%) is tied to substantially lower risks of several obesity-related conditions—osteoarthritis (37%), CKD (30%), sleep apnea (69%), and heart failure (32%)—though the heart failure result wasn’t statistically robust. About half of participants stopped treatment within a year, and the findings imply that health benefits depend on achieving and maintaining weight loss, not just the drugs themselves.

via ScienceAlert|
#bmi#disease-risk#glp-1-drugs
Ozempic May Rewire the Brain, Changing Mood, Motivation and Cravings
science15 hours ago

Ozempic May Rewire the Brain, Changing Mood, Motivation and Cravings

New research suggests GLP-1 drugs like Ozempic—used for obesity and diabetes—may reshape brain networks and influence appetite, mood, cognition and addiction. Early brain scans in teens and young women on GLP-1s showed increased connectivity in the salience network within months, hinting at direct neural effects or indirect changes via gut-brain pathways. Scientists are exploring roles beyond weight loss, including potential impacts on anxiety, compulsive thinking and addiction, while noting that long-term, developmental effects (especially in adolescents) remain unclear. Although some trials hint at neuroprotective signals, a major Alzheimer’s trial with a related drug failed to slow cognitive decline, underscoring that conclusions about brain health from GLP-1s are still uncertain and ongoing.

via Yahoo|
#addiction#brain-networks#glp-1-drugs
GLP-1 Weight-Loss Drugs Show Potential to Slow Cancer Spread in Real-World Study
health1 day ago

GLP-1 Weight-Loss Drugs Show Potential to Slow Cancer Spread in Real-World Study

A Cleveland Clinic retrospective study involving more than 12,000 patients suggests GLP-1 weight‑loss drugs (e.g., semaglutide, tirzepatide, dulaglutide, liraglutide, lixisenatide, pramlintide) may slow progression to advanced disease for several obesity‑related cancers (lung, breast, colorectal, liver), compared with DPP‑4 inhibitors. In four solid tumors, GLP‑1 users showed notably lower progression to stage 4 (up to 50% in non‑small cell lung cancer, 43% breast, 31% colorectal, 38% liver); prostate, pancreatic, and kidney cancers showed non‑significant trends. Tumors with higher GLP‑1 receptor expression also correlated with better survival. The study is not peer‑reviewed and cannot prove causation; randomized trials are needed to confirm mechanisms and effects.

via Fox News|
#asco-conference#cancer-progression#glp-1-drugs
GLP-1 Drugs Spark Unexpected Fragrance Obsession
wellness11 days ago

GLP-1 Drugs Spark Unexpected Fragrance Obsession

As GLP-1 medications used for weight loss (e.g., Ozempic, Wegovy, Mounjaro) help quiet food cues, some users report a heightened obsession with fragrances and stronger scent perception. Experts suggest reduced food reward may make non-food senses more salient, potentially involving GLP-1 receptors in the olfactory system; while anecdotes are growing, large controlled studies are still needed. A few FAERS reports mention parosmia, which could also influence fragrance preferences.

via HuffPost|
#fragrance#glp-1-drugs#scent-sensitivity
On Holding tops estimates as premium strategy pays off; Hims & Hers posts surprise loss, shares slide
business17 days ago

On Holding tops estimates as premium strategy pays off; Hims & Hers posts surprise loss, shares slide

On Holding beat Wall Street with $1.07B revenue and $0.40 adjusted EPS for Q1 2026, and lifted profitability targets to at least 64.5% gross margin and 19.5–20% EBITDA margin for 2026. In contrast, Hims & Hers Health swung to a Q1 net loss of $92.1M (−$0.40 per share) on $608M revenue, missing estimates, as it pivots to branded GLP-1 products and partners with Novo Nordisk; the stock fell about 8% after hours amid the weaker results.

via Yahoo Finance Singapore|
#after-hours-reaction#business#earnings
GLP-1 diabetes medicines show potential to curb Alzheimer's protein buildup in preclinical studies
health1 month ago

GLP-1 diabetes medicines show potential to curb Alzheimer's protein buildup in preclinical studies

A new review of mostly preclinical studies links GLP-1 diabetes/weight-loss medications (e.g., semaglutide, liraglutide) to reduced amyloid-beta plaques and tau tangles in cells and animals, with only two small human trials reporting mixed results; still early evidence and larger clinical trials are needed to confirm cognitive benefits.

via ScienceAlert|
#alzheimers-disease#amyloid-beta#clinical-trials
Experts warn: 5 key missteps when using GLP-1 weight-loss drugs
health1 month ago

Experts warn: 5 key missteps when using GLP-1 weight-loss drugs

GLP-1 medications such as semaglutide and tirzepatide can aid weight loss and may improve cardiovascular and kidney health, but misuse can undermine results or cause harm. Doctors warn of five common mistakes: skipping labs or ignoring underlying health issues, poor nutrition or inadequate protein, cutting calories without adequate protein, increasing GLP-1 doses too quickly, and obtaining medications online without medical oversight. For best results, get a medical evaluation with labs first, monitor fat loss versus lean mass monthly, maintain a protein-rich balanced diet with smaller meals, and titrate doses gradually to minimize side effects and risks like pancreatitis.

via AOL.com|
#dosing#glp-1-drugs#health
GLP-1 Weight-Loss Drugs Deliver Big Wins, But With Notable New Risks
health1 month ago

GLP-1 Weight-Loss Drugs Deliver Big Wins, But With Notable New Risks

GLP-1 medications used for obesity and diabetes (e.g., Wegovy, Ozempic, Mounjaro, Zepbound) have driven substantial weight loss and improved health markers, with reports of cardiovascular risk reduction and liver disease improvements; some studies also hint at benefits for fertility, cancer risk, and possibly aging-related conditions, while research continues. However, these drugs can cause drawbacks such as hair thinning, excess skin, muscle and bone loss, gallbladder issues, vision changes, and dental concerns. Experts emphasize slow, steady weight loss, adequate nutrition, and careful monitoring as more long-term effects are studied.

via Sun Sentinel|
#cardiovascular-health#glp-1-drugs#health
Endoscopic gut reset may lock in GLP-1 weight loss after stopping meds
health1 month ago

Endoscopic gut reset may lock in GLP-1 weight loss after stopping meds

A minimally invasive endoscopic procedure called duodenal mucosal resurfacing may help people maintain weight loss after discontinuing GLP-1 diabetes/weight-loss drugs. In a six‑month follow‑up of 45 participants (29 treated, 16 sham) who had at least 15% weight loss on tirzepatide, the procedure group regained about seven pounds and kept over 80% of their drug‑induced weight loss, while the sham group regained more, suggesting a durable metabolic reset observed at Digestive Disease Week 2026.

via AOL.com|
#duodenal-mucosal-resurfacing#glp-1-drugs#health
Reddit AI Scan Flags Potentially Hidden Side Effects in GLP-1 Weight-Loss Drugs
health1 month ago

Reddit AI Scan Flags Potentially Hidden Side Effects in GLP-1 Weight-Loss Drugs

AI analyzed over 400,000 Reddit posts from about 70,000 users over five years to surface patient-reported side effects of GLP-1 medications (including semaglutide and tirzepatide). While many reported issues align with known effects, the study highlights potentially underreported symptoms such as menstrual irregularities and temperature-related changes, suggesting online patient discussions can provide early safety signals. Causation isn’t established, and researchers advocate broader, multilingual follow-up beyond Reddit to validate findings and inform clinicians.

via SciTechDaily|
#drug-safety#glp-1-drugs#health
Body positivity endures as slimming trends rise with GLP-1 era
health2 months ago

Body positivity endures as slimming trends rise with GLP-1 era

A Axios piece argues the body positivity movement remains vital even as a GLP-1–driven slimming trend and celebrity focus dominate media, risking a return to thin-ideal norms. Experts warn this creates a two-tier world where access to medical weight interventions shapes self-perception and mental health, while activists emphasize reframing GLP-1s as disease-treating tools rather than vanity products. The fight for body diversity is framed as a social-justice issue that remains ongoing despite changing trends.

via Axios|
#body-image#body-positivity#glp-1-drugs
Heart protection from GLP-1 drugs fades quickly after stopping, study finds
health2 months ago

Heart protection from GLP-1 drugs fades quickly after stopping, study finds

A Washington University study of more than 333,000 U.S. veterans with type 2 diabetes found that continuous GLP-1 therapy reduced cardiovascular risk by about 18% after three years; stopping the medication for six months raised risk by 4%, after one year by 14%, and after two years by 22%, with restarting yielding only partial protection, highlighting the importance of long‑term use and accompanying lifestyle changes.

via AOL.com|
#bmj-medicine#cardiovascular-risk#glp-1-drugs
GLP-1 Weight-Loss Drugs Reveal Hidden Costs Beyond the Scale
health2 months ago

GLP-1 Weight-Loss Drugs Reveal Hidden Costs Beyond the Scale

A BuzzFeed Health feature examines how GLP-1 weight-loss medications (like Ozempic, Wegovy and Mounjaro) marketed for medical use are being used cosmetically, triggering a viral Reddit thread about a partner whose two-year Ozempic journey left her with a gaunt appearance, muscle loss, debt, and relationship strain. The piece highlights easy access via telehealth, aggressive marketing, and the risk of body dysmorphia or eating disorders when medical safeguards are bypassed. It emphasizes that these drugs are not miracle cures and should be paired with resistance training and adequate protein, while urging professional support for underlying psychological issues and broader societal pressures around body image.

via BuzzFeed|
#body-dysmorphia#glp-1-drugs#health