The downside of weight loss drugs: muscle loss.

Weight loss drugs can lead to loss of lean mass, including muscle, which can decrease resting metabolic rate and affect overall health. However, studies have shown that at the end of the weight loss period, people may have a healthier body composition with a higher ratio of lean mass to fat. To mitigate lean mass loss, it is important to eat enough protein and engage in resistance training. People on weight loss drugs should stay in close contact with their healthcare team to monitor muscle loss, kidney function, and electrolyte levels. There are currently no guidelines for physicians counseling patients on weight loss drugs.