Tag

Metabolism

All articles tagged with #metabolism

nutrition2 hours ago•10 min saved

Sweeteners Across Generations: Gut Microbes and Metabolism Affected by Sucralose and Stevia in Mice

A mouse study in Frontiers in Nutrition shows artificial (sucralose) and natural (stevia) non-nutritive sweeteners can alter the gut microbiome and gene expression related to inflammation and metabolism, with effects passing to a second generation: sucralose impaired glucose tolerance in male offspring in generation 1, and by generation 2, fasting glucose rose in male sucralose descendants and female stevia descendants, while both sweeteners lowered short-chain fatty acids and increased microbial diversity. The researchers caution that results in mice may not translate to humans and call for moderation and further study.

via News-Medical|

#epigenetics #generations #gut-microbiome

science-and-technology7 hours ago•6 min saved

Sugar Substitutes Under Scrutiny: Do They Really Help Health?

New research questions whether sugar substitutes truly deliver health benefits; despite being marketed to cut calories and prevent tooth decay, emerging evidence suggests potential downsides and calls for long-term studies to weigh risks and benefits.

via The Economist|

#artificial-sweeteners #dental-health #health-effects

science1 day ago•8 min saved

Diet–Gut Signals Flip White Fat into Calorie-Burning Beige Fat in Mice

Researchers found that a low-protein diet activates a specific gut‑bacteria community that emits signals causing white fat to become beige, calorie‑burning fat in mice. Four bacterial strains are needed, and the effect relies on a two‑step process: changes in bile acids push fat cells toward burning energy, and the liver releases FGF21 to boost metabolism. The effect disappears if either signal is blocked, showing the microbiome’s diet‑interpreting role. While promising for metabolic disease targets, human applicability remains unproven and the diet used isn’t recommended for people; the work points to pathways for therapies that mimic these microbial signals rather than extreme diets or probiotics alone.

via SciTechDaily|

#beige-adipocytes #fat-browning #gut-microbiome

science2 days ago•8 min saved

Centenarians’ Blood Signatures Hint at Slower Aging

A Swiss study analyzing blood from centenarians (100–105) found 37 of 724 serum proteins resemble those of younger people, suggesting key aging mechanisms can slow rather than stop; centenarians show lower oxidative stress markers, more youthful extracellular-matrix proteins, and a metabolism that remains balanced, with lifestyle factors highlighted as a powerful longevity lever.

via SciTechDaily|

#aging #centenarians #longevity

science14 days ago•5 min saved

Aronia Juice's Metabolic Boost Depends on Your Gut Microbiome

A study using humanized mice found polyphenol-rich Aronia juice can shield against high-fat-diet–induced metabolic disruption, but benefits vary with the gut microbiome: mice with low-inflammatory microbiomes showed preserved gut diversity and favorable metabolic markers after Aronia treatment, while those with high-inflammatory microbiomes did not exhibit the same benefits.

via Indian Defence Review|

#aronia-juice #gut-microbiome #inflammation

health17 days ago•23 min saved

Python Metabolite Sparks GLP-1–Free Weight Loss Hint

Scientists from CU Boulder and Stanford identified a python-derived gut metabolite, para‑tyramine‑O‑sulfate (pTOS), that after being tested in mice triggered weight loss through hypothalamic pathways without muscle or energy loss, suggesting a potential natural alternative to GLP‑1 weight‑loss drugs and prompting Arkana Therapeutics to pursue a synthetic version.

via New York Post|

#glp-1 #health #metabolism

health29 days ago•7 min saved

Berberine Isn’t a Natural Ozempic; It Modulates the Gut Microbiome

A new review says berberine isn’t a universal metabolic fix or a hormone-like drug; it mostly acts in the gut by shaping microbiota, inflammation, and the intestinal barrier, with effects that vary by individual gut ecosystems. Its low bioavailability keeps activity local to the intestine, where microbiota may convert it into active compounds. It should be used under medical supervision due to safety concerns and drug interactions, not as a replacement for prescribed meds.

via SciTechDaily|

#berberine #bioavailability #gut-brain-axis

science1 month ago•10 min saved

Energy as a Guiding Principle for Biomedicine

An essay argues for embedding energy dynamics into biomedicine—finite energy budgets, trade-offs, and cross-species principles—to better explain aging, cancer, immune responses, and other diseases, and to uncover new treatment avenues alongside traditional molecular biology.

via Nature|

#biomedicine #disease #energy

health1 month ago•4 min saved

Hormone Balance Hacks: Sleep Better, Burn More, and Feel Calmer Naturally

Endocrinologist Dr. Gaurav Mandal outlines six drug-free strategies to rebalance hormones that influence sleep, metabolism and mood: start with morning light to synchronize your circadian rhythm; schedule morning workouts when cortisol is highest; time eating and caffeine within a 10-hour window (roughly 8 a.m.–6 p.m.) and front-load calories at breakfast and lunch on a Mediterranean-style diet with three regular meals; stay well hydrated; prioritize social touch (hugs) to boost oxytocin; reduce screen time before bed to raise melatonin and aim for 7–9 hours of sleep, ideally before midnight, for better rest and hormonal balance.

via New York Post|

#circadian-rhythm #diet #health

health-and-medicine1 month ago•6 min saved

Ketogenic diet boosts exercise adaptation in hyperglycemic mice

In mice with high blood sugar, a high-fat ketogenic diet normalized blood sugar within a week and remodeled muscles to be more oxidative, improving oxygen use and endurance during exercise, suggesting diet and exercise may synergize to boost metabolic health—though human studies are needed and keto can be hard to maintain.

via ScienceDaily|

#exercise-performance #health-and-medicine #hyperglycemia

health1 month ago•6 min saved

Women, Lift Strong: How Strength Training Boosts Metabolism, Hormones and Bone Health

Nutritionist Nmami Agarwal explains that strength training, which can be done without a gym, builds muscle, ligaments, and bone density while improving metabolism and insulin sensitivity, supporting hormonal balance and reducing injury risk—empowering women to become metabolically smarter, hormonally happier, and physically stronger.

via NDTV|

#bone-density #health #insulin-sensitivity

health1 month ago•10 min saved

Sunrise Sweat: 5 Morning Moves to Trim Belly Fat After 55

Five morning, full‑body exercises are recommended over crunches for shedding belly fat after 55: dumbbell squat-to-overhead press, reverse lunges, walkouts/inchworms, kettlebell swings, and mountain climbers. These compound moves engage large muscle groups to spike metabolism and reduce visceral fat, reinforcing that fat loss requires overall body fat reduction rather than spot‑training.

via Eat This Not That|

#aging-fitness #belly-fat #health

health1 month ago•11 min saved

Debunking the 'fast' vs 'slow' metabolism myth: weight isn’t dictated by a single rate

The article explains that metabolism is a mix of basal energy use, digestion, daily movements, and exercise, not simply a ‘fast’ or ‘slow’ label. Hypermetabolism can occur with certain conditions (e.g., hyperthyroidism), while hypothyroidism and PCOS can slow resting energy use. Weight changes arise from multiple interacting factors—genetics, eating habits, activity, and sleep—so most healthy people don’t have drastic, lasting highs or lows in metabolic rate.

via The Conversation|

#health #hypermetabolism #hypothyroidism

science1 month ago•5 min saved

GLP-1 Drug Semaglutide Shows Weight-Loss-Independent Joint Repair in Osteoarthritis

A new study indicates semaglutide may repair osteoarthritis damage by reprogramming cartilage-cell energy metabolism via the GLP-1R–AMPK–PFKFB3 axis, with mouse data showing protection beyond weight loss and a small human trial (HA + semaglutide) reporting reduced pain and thicker cartilage—suggesting a weight-loss–independent mechanism that requires further clinical validation.

via ScienceAlert|

#chondrocytes #glp-1 #metabolism

animals1 month ago•71 min saved

The Chill Switch: How Some Animals Control Body Heat to Weather Extremes

Some mammals and birds can deliberately alter their internal temperature through heterothermy, using short bouts of torpor or longer hibernation to conserve energy and water during harsh weather, predators, or food shortages. Studies highlight bats, sugar gliders, dormice, and other species adjusting torpor in response to wind, rain, predators, and even moon phase, showing a flexible survival strategy beyond normal body temperature control. This helps them endure variability, though it isn’t a foolproof shield against climate change.

via Live Science|

#animals #heterothermy #hibernation