The Impact of Weight Loss and Gain Medications on Your Body.

TL;DR Summary
Weight loss drugs can lead to the loss of lean mass, including muscle, which can decrease resting metabolic rate and affect overall health. However, at the end of the weight loss period, people may have a healthier body composition with a higher ratio of lean mass to fat. To mitigate lean mass loss, people should eat enough protein and engage in resistance training. Physicians need research-backed recommendations for counseling patients on weight loss drugs, especially for older people.
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