Migraine breakthrough: CGRP, brain signals, and smarter relief

Migraines are now understood as a primary neurological disorder driven by trigeminovascular activation and CGRP release, unfolding through four phases—prodrome, aura, migraine attack, and postdrome. Advances in CGRP-targeted therapies (gepants and monoclonal antibodies) have transformed care, though cost and access remain barriers. Lifestyle factors like sleep, dehydration, and stress influence susceptibility, and myth about foods causing migraines has been debunked.