Tag

Migraine

All articles tagged with #migraine

New Study Links CGRP Migraine Injectables to 40% Higher Miscarriage Risk
health10 hours ago

New Study Links CGRP Migraine Injectables to 40% Higher Miscarriage Risk

A new observational study published in JAMA Neurology indicates that exposure to CGRP-targeted monoclonal antibodies, a class of injectable migraine preventatives approved in 2018, is associated with a 40% increased risk of spontaneous abortion in the first 20 weeks of pregnancy. The research, led by Anick Bérard, analyzed data from 7,579 pregnancies among commercially insured US women between 2018 and 2021. While the study found a significant association between these drugs and miscarriage, it did not establish causation, noting that severe migraine itself may contribute to the risk. In contrast, exposure to propranolol, another migraine preventive, showed no increased risk. Clinicians are urged to counsel patients of reproductive age on these potential risks while awaiting further safety data.

Cardiologist Links Beetroot Supplements to Severe Neurologic Symptoms
health-and-medicine12 hours ago

Cardiologist Links Beetroot Supplements to Severe Neurologic Symptoms

Dr. Melissa Walton-Shirley, a retired cardiologist, details her personal experience using beetroot supplements to manage resistant hypertension. While initial studies suggest beetroot can lower blood pressure by boosting nitric oxide, her case highlights potential risks. She developed severe neurologic symptoms, including ataxia and visual disturbances, which resolved after stopping the supplements. She attributes this to the trigeminovascular cascade triggered by increased cyclic guanosine monophosphate (cGMP). The article serves as a cautionary tale for patients and clinicians regarding over-the-counter nitrate sources.

Neurologists Validate Viral Eyebrow Clip Hack as Temporary Pain Relief
health12 days ago

Neurologists Validate Viral Eyebrow Clip Hack as Temporary Pain Relief

A viral social media trend suggesting that placing a claw clip on the eyebrow can alleviate migraine pain has drawn attention from medical experts. While not a cure, neurologists explain that the method may offer temporary relief by stimulating the trigeminal nerve and diverting attention from pain signals. However, experts caution that the effect is transient, varies by individual, and should not replace prescribed treatments.

New Study Links Macromastia to Migraines, Neck Pain, and Sleep Apnea
health19 days ago

New Study Links Macromastia to Migraines, Neck Pain, and Sleep Apnea

A new study published in Headache: The Journal of Head and Face Pain finds that women with macromastia (enlarged breasts) have significantly higher rates of chronic migraine, neck pain, cervical radiculopathy, and obstructive sleep apnea. The retrospective analysis of 687 women at Stanford Medical Center clinics showed that macromastia was associated with a 40% higher prevalence of chronic migraine, double the rate of neck pain, and a 54% higher likelihood of sleep apnea. While the study does not prove causation, it suggests that macromastia may contribute to broader health issues beyond physical discomfort. Lead author Kristyn Pocock emphasizes the need for comprehensive evaluations for women experiencing these symptoms. Preliminary evidence indicates that breast reduction surgery may help alleviate some symptoms, but larger studies are needed to confirm these benefits.

Pharmacists to treat 12 common conditions on the spot in England this autumn
health1 month ago

Pharmacists to treat 12 common conditions on the spot in England this autumn

England will let local pharmacies treat 12 common conditions on the spot this autumn, expanding the existing Pharmacy First service (which currently covers seven) to include migraines, acne, scabies, ear infections and badly blocked noses; the move aims to ease GP and A&E pressures and speed access, with a phased rollout starting in hundreds of pharmacies and expanding to thousands. Pharmacy leaders say funding may not cover the extra workload, though the scheme has already delivered millions of consultations since 2024.

US Guidelines Broaden Migraine Prevention to More Patients
health1 month ago

US Guidelines Broaden Migraine Prevention to More Patients

US neurologists have updated the 2012 AAN/AHS migraine guidelines, recommending preventive treatment for patients with four or more moderate-to-severe headaches per month or substantial migraine-related disability. The update endorses newer CGRP-targeting drugs (atogepant, erenumab, fremanezumab, galcanezumab, eptinezumab) as first-line options and adds Botox for chronic migraine, while recognizing additional options like propranolol, topiramate, valproate, and amitriptyline in specific cases. Because responses vary and side effects occur, multiple treatments may be tried. The guidelines are non-binding but intended as a resource to improve access to effective prevention; after about six months of preventive therapy, clinicians should discuss tapering and potential rebound risks.

New Migraine Prevention Guidelines Highlight CGRP Therapies and Personalization
health1 month ago

New Migraine Prevention Guidelines Highlight CGRP Therapies and Personalization

The American Academy of Neurology and the American Headache Society released updated migraine prevention guidelines that incorporate CGRP-targeted therapies and emphasize individualized treatment decisions based on efficacy, tolerability, long-term safety, and cost for episodic and chronic migraine. The guideline expands recommendations to more patients (those with frequent migraine days) and outlines preferred options (atogepant, CGRP monoclonal antibodies, and onabotulinumtoxinA, alongside older meds like propranolol, topiramate, and valproate). It also provides guidance on trial duration (8–12 weeks for most meds, 24 weeks for onabotulinumtoxinA), pregnancy considerations, comorbidities, medication overuse, and nonpharmacologic approaches to optimize care.

AI Reveals Migraine as a Spectrum with Distinct Subtypes
health1 month ago

AI Reveals Migraine as a Spectrum with Distinct Subtypes

Researchers used machine learning on data from 43,197 Norwegians to identify migraine signatures beyond headache symptoms, achieving strong discrimination (AUC ~0.80) without relying on traditional headache criteria. The study suggests migraine is a spectrum with four subgroups and distinct genetic signals, where age, neck pain, menstruation and nausea were key predictors; genetics offered only modest gains, hinting at personalized treatments in the future.

Hidden Ailments: 25 Conditions Dismissed Yet Devastating
health1 month ago

Hidden Ailments: 25 Conditions Dismissed Yet Devastating

A BuzzFeed/Yahoo Health piece compiles 25 firsthand accounts of illnesses that are often dismissed as “just pain,” highlighting conditions from IBS with anxiety and celiac disease to chronic migraines, endometriosis, chronic fatigue syndrome and Ehlers-Danlos, showing how these conditions profoundly disrupt daily life and underscoring the need for validation, better care, and support for the people living with them.

Migraine Over Dog Walk: A Teen's Struggle Between Family Duty and Partner Care
life-and-drama2 months ago

Migraine Over Dog Walk: A Teen's Struggle Between Family Duty and Partner Care

A 19-year-old man declines to wake his girlfriend, who has a migraine, to walk the family dog. He offers to wash the dishes instead, but his parents call him immature and manipulative. He argues that he doesn’t want to wake her and would rather help later, illustrating the tension between family obligations and caring for a partner, with readers weighing who’s in the right.

Migraine breakthrough: CGRP, brain signals, and smarter relief
life-and-style2 months ago

Migraine breakthrough: CGRP, brain signals, and smarter relief

Migraines are now understood as a primary neurological disorder driven by trigeminovascular activation and CGRP release, unfolding through four phases—prodrome, aura, migraine attack, and postdrome. Advances in CGRP-targeted therapies (gepants and monoclonal antibodies) have transformed care, though cost and access remain barriers. Lifestyle factors like sleep, dehydration, and stress influence susceptibility, and myth about foods causing migraines has been debunked.

ADHD tied to chronic pain and a spectrum of health risks
health-and-wellness4 months ago

ADHD tied to chronic pain and a spectrum of health risks

A Washington Post Well+Being piece reports that ADHD is linked with a range of health issues beyond core symptoms, including anxiety, disordered eating, migraines, and long COVID, with chronic pain highlighted as part of the broader comorbidity picture; findings underscore the need for holistic screening and further research into shared mechanisms.