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EBV-Driven CD4+ T Cells Link Epstein-Barr Virus to MS, Opening Immunotherapy Avenues

1 min read
Source: Nature
EBV-Driven CD4+ T Cells Link Epstein-Barr Virus to MS, Opening Immunotherapy Avenues
Photo: Nature
TL;DR Summary

New research shows Epstein–Barr virus activates CD4+ T cells that attack nerve insulation in multiple sclerosis, and that anti-CD20 therapies (which reduce B cells and viral stimuli) lower CD4+ T-cell responses and EBV activity—hinting immunotherapies could slow relapses and progression.

Topics:health#anti-cd20-therapy#cd4-t-cells#epstein-barr-virus#frexalimab#multiple-sclerosis#science
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  1. Biologists pinpoint how common virus triggers multiple sclerosis  Nature
  2. From ‘kissing disease’ to MS: Harvard study uncovers how a common virus triggers multiple sclerosis  The Boston Globe
  3. Best treatment for multiple sclerosis may be antivirals  New Scientist
  4. New study untangles how Epstein-Barr viral infection triggers immune response in multiple sclerosis  STAT
  5. Epstein-Barr virus components linked to the development of multiple sclerosis have been identified  Science Media Centre España

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