Full-plant cannabis extract improves glucose tolerance in mice, unlike THC alone

In a mouse study, obese mice on a high-fat, high-sugar diet treated with THC lost weight and body fat, but only those given a full-plant cannabis extract showed improved glucose tolerance; THC alone did not yield this metabolic benefit, suggesting other cannabis compounds drive the positive effects. The work, published in The Journal of Physiology, cautions against drawing human conclusions and highlights the need for further research into non-THC cannabinoids like CBG and other plant compounds.