Genetically Edited Pig Kidney Acts as Nine-Month Bridge to Human Transplant

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Source: The Guardian
Genetically Edited Pig Kidney Acts as Nine-Month Bridge to Human Transplant
Photo: The Guardian
TL;DR Summary

Doctors used a genetically engineered pig kidney (Wilma) to keep a 66-year-old man alive for 271 days—nine months—without dialysis, serving as a bridge to a human kidney transplant; the pig had 69 genome edits to reduce rejection and virus risk, and no pig pathogens were detected, but the kidney eventually failed and he later received a human donor kidney; this world-first case suggests xenotransplantation could alleviate the organ shortage but requires more trials.

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