NAD+, NMN, and Resveratrol: Plausible Biology, Limited Human Evidence

The article explains that NAD+, its precursors NMN and NR, and the polyphenol resveratrol touch aging biology, but human evidence for real anti-aging benefits is limited. NAD+ is vital for energy, DNA repair, and stress responses and declines with age; precursors can raise NAD+ levels in blood or tissues, yet clear, meaningful clinical effects are not established. Resveratrol shows lab promise but suffers from poor oral bioavailability and mixed human results. Overall, biology is plausible but marketing often implies youth, whereas proven anti-aging benefits from supplements are not yet demonstrated; recommended healthy-aging strategies remain regular exercise, good sleep, balanced diet, and managing health conditions. (Republished from The Conversation.)