New Insights into NMDA Receptor Regulation and Neurosteroid Binding

TL;DR
This article presents cryo-EM structures revealing the mechanisms of conductance regulation and neurosteroid binding in NMDA receptors, highlighting different conformational states and the effects of neurosteroids like 24S-HC and EU1622-240 on receptor function.
Topics:healthscience#conductance-control#cryo-em#neurosteroid-binding#nmda-receptors#science#structural-biology
- Mechanism of conductance control and neurosteroid binding in NMDA receptors Nature
- A doorstop for the brain’s electrical gates Cold Spring Harbor Laboratory
- How the Brain’s Ion Gates Open and Close Neuroscience News
- Brain’s Electrical Gates Get a New Doorstop: A Scientific Breakthrough Bioengineer.org
- Controlling NMDA Receptors: Conductance and Neurosteroids Bioengineer.org
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