Nose injuries may let bacteria reach the brain, hinting at Alzheimer’s link in mice

1 min read
Source: Indian Defence Review
Nose injuries may let bacteria reach the brain, hinting at Alzheimer’s link in mice
Photo: Indian Defence Review
TL;DR

Australian researchers in Griffith University show, in mice, that Chlamydia pneumoniae can travel from the nasal cavity to the brain via the olfactory and trigeminal nerves, with amyloid-beta deposits forming within days. Nasal epithelial injury increased bacterial load and brain involvement, but there are no human data yet and the causal role for Alzheimer's remains unproven; a human study is planned.

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