Obesity Leaves a Lasting Immune Memory After Weight Loss
TL;DR Summary
A decade-long study shows that obesity can leave a persistent “memory” in both fat and immune cells through DNA methylation, sustaining inflammation and higher risk for obesity-related diseases even after weight loss. Maintaining weight loss for about five to ten years may gradually erode this memory, underscoring why relapse is common and highlighting potential therapies such as SGLT2 inhibitors to reverse obesity’s immune effects.
- Immune Cells 'Remember' Obesity Long After Weight Loss, Study Finds ScienceAlert
- How to remove a metabolic tattoo EurekAlert!
- Weight Loss: You lost the weight: So why does your body still think you are obese? The Times of India
- Obesity may leave immune cells stuck in inflammatory mode after weight loss News-Medical
- Weight loss may not erase obesity’s impact on immune cells Earth.com
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