
Obesity Leaves a Lasting Immune Memory After Weight Loss
A decade-long study shows that obesity can leave a persistent “memory” in both fat and immune cells through DNA methylation, sustaining inflammation and higher risk for obesity-related diseases even after weight loss. Maintaining weight loss for about five to ten years may gradually erode this memory, underscoring why relapse is common and highlighting potential therapies such as SGLT2 inhibitors to reverse obesity’s immune effects.












