OSU’s Nanoparticles Target Lung Tumors and Muscle Wasting

Oregon State University researchers report lipid nanoparticles that bind vitronectin in the bloodstream to home in on lung tumors and deliver follistatin mRNA, reducing tumor burden about 2.5-fold more than conventional LNPs in mice, while also countering cancer cachexia by preserving appetite, weight, and muscle—preclinical results with human testing to come.