Psychedelics reshape brain networks, revealing an 'embedded' sense of self

TL;DR
A Nature study with 62 healthy adults shows psilocybin reorganizes brain networks across rest, mindfulness-like states, music, and cloud-watching, reducing the usual separation between self and world and revealing an 'embeddedness' signature that correlates with next-day positive changes. Using MRI/EEG and machine-learning mapped patterns, the research highlights context’s role in psychedelic experiences while noting limitations: participants were healthy volunteers, study was open-label and lacked a placebo, and results may not generalize to patients.
- New research shows how psychedelics reorganise the patterns in your brain theconversation.com
- Psychedelics align brain activity with context Nature
- How psilocybin alters consciousness to create a sense of ‘oneness’ Scientific American
- Landmark study upends how we think the brain responds to psychedelics New Atlas
- World's largest psilocybin brain-imaging study maps how context reshapes psychedelic effects Medical Xpress
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