Tag

Embeddedness

All articles tagged with #embeddedness

Psychedelics reshape brain networks, revealing an 'embedded' sense of self
science15 minutes ago

Psychedelics reshape brain networks, revealing an 'embedded' sense of self

A Nature study with 62 healthy adults shows psilocybin reorganizes brain networks across rest, mindfulness-like states, music, and cloud-watching, reducing the usual separation between self and world and revealing an 'embeddedness' signature that correlates with next-day positive changes. Using MRI/EEG and machine-learning mapped patterns, the research highlights context’s role in psychedelic experiences while noting limitations: participants were healthy volunteers, study was open-label and lacked a placebo, and results may not generalize to patients.

Psilocybin reshapes brain dynamics to mirror context and cue lasting change
science2 hours ago

Psilocybin reshapes brain dynamics to mirror context and cue lasting change

In a large, single-site study, 62 participants underwent fMRI and EEG during rest and naturalistic contexts (meditation, music, movie) before and after psilocybin. The drug reorganizes brain activity into context-aligned, low-dimensional trajectories, increasing global integration in associative regions and decreasing it in sensory areas during eyes-closed states, with eyes-open movie boosting overall synchrony. Machine-learning embeddings reveal a context-dependent state—embeddedness—that correlates with the depth of subjective self-/boundary-dissolution and with next-day mindset change; music amplified effects, while mindfulness training did not alter acute network measures. The work links latent neural order to subjective experience and therapeutic potential by showing how context shapes psychedelic brain dynamics.