Serotonin May Amplify Tinnitus Through a Specific Brain Circuit

A new mouse study links serotonin to tinnitus by triggering a dedicated brain circuit that connects to the auditory system; increasing serotonin worsens tinnitus-like behaviors, while silencing that circuit reduces them, suggesting future treatments could separate mood benefits from tinnitus side effects caused by serotonin-boosting drugs like SSRIs.