Uncovering the Cause of Gray Hair: Stuck Stem Cells

TL;DR
Melanocyte stem cells (McSCs) lose their ability to move between hair follicle compartments as people age, leading to hair graying. McSCs are plastic, meaning they continually shift between maturity stages and compartments within hair follicles. However, as hair ages and regrows repeatedly, more McSCs become stuck in the hair follicle bulge and are unable to mature into pigment-producing cells. Restoring McSC motility or moving them back to their germ compartment could potentially reverse or prevent hair graying in humans.
- Why Does Hair Turn Gray? Research Uncovers Role of “Stuck” Stem Cells SciTechDaily
- Researchers may have discovered what causes hair to go gray TODAY
- Scientists May Have Finally Worked Out Why Hair Turns Gray – And Possibly How to Stop It ScienceAlert
- Researchers find "stuck" stem cells may cause graying hair Yahoo! Voices
- Why Do We Go Grey As We Age? Healthnews.com
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