Tag

Stem Cells

All articles tagged with #stem cells

science9 days ago•5 min saved

Aging Blood Stem Cells May Spark Inflammation Across the Body

New mouse studies show aging blood stem cells can drive inflammation in distant tissues by producing inflammatory immune cells. Boosting SIRT3 in these cells reduced inflammatory outputs and improved mobility, metabolic control, and lung health; transferring these immune cells to other mice conveyed similar benefits. Findings are preliminary and in animals, so it’s not yet clear if humans share the mechanism or if SIRT3 could be a therapeutic target for aging.

via sciencealert.com|

#aging #immune-system #inflammation

science1 month ago•5 min saved

Gentle stem-cell transplant hints at rejuvenating aging blood and immunity in mice

A study in mice shows that transplanting young, lab-expanded blood-forming stem cells into aged animals—without chemotherapy or radiation—restores blood production and rebirths of immune cells (naive B and T cells), effectively reshaping the aging immune system. While the approach worked in mice and used a gentler method (including targeted helpers to spare healthy cells), it is far from clinical use in humans and faces safety, regulatory, and scalability hurdles; nonetheless, experts see potential for future therapies that renew the body’s blood-forming system rather than wide-ranging anti-aging cures.

via SciTechDaily|

#aging #immune-system #regenerative-medicine

science1 month ago•15 min saved

Regenerating Teeth: Scientists Aim to Grow a Living Tooth

Researchers are pursuing regenerative dentistry to regrow teeth using stem cells and tissue engineering, aiming to replace fillings and implants with living tooth tissue; early work has yielded enamel- and dentine-forming cells that can create tooth-like organs and even lab-grown teeth in animal models, but practical human application is years away and will require safer, more advanced environments before trials.

via BBC|

#dental-health #lab-grown-teeth #regenerative-dentistry

health1 month ago•9 min saved

Immune-engineered stem cells aim for functional cure in type 1 diabetes

Researchers at the ISSCR 2026 meeting report a first-in-human approach using hypoimmune, allogeneic insulin-producing cells that may persist and function without lifelong immunosuppression, potentially moving cell replacement therapies for type 1 diabetes toward a functional cure; durability and scalability remain key questions.

via News-Medical|

#diabetes #health #hypoimmune-engineering

science1 month ago•7 min saved

Lab-grown human sperm advances in mice, but full maturity remains elusive

Researchers transplanted human iPS-derived immature cells into a mouse kidney pouch, where they self-organized into early sperm-supporting structures and developed into spermatogonia after six months. While this marks progress toward lab-made sperm, the cells did not mature yet, signaling further hurdles. The work offers a new avenue to study early human sperm development and infertility, though clinical applications are far off and raise ethical questions about future reproductive technologies.

via Nature|

#bioethics #infertility #lab-grown-sperm

science1 month ago•42 min saved

Lab-grown retinal vessels restore function in mice, fueling hope for blindness treatments

Duke University researchers used induced pluripotent stem cells (iPSCs) to grow retinal endothelial cells—the vessels lining the retina—and demonstrated they can form functional vascular networks in lab conditions. When injected into mouse models of retinal disease, the lab-grown cells integrated with existing tissue to rebuild blood vessels and restore retinal function, suggesting a cheaper, scalable path toward preventative therapies for conditions like diabetic retinopathy.

via Good News Network|

#diabetic-retinopathy #ipscs #retina

health-and-medicine1 month ago•7 min saved

Aging Muscle Stem Cells: Speedy Repair Comes at a Survival Cost

UCLA researchers found aging muscle stem cells accumulate the protein NDRG1, which slows repair by dampening mTOR signaling, but blocking NDRG1 reactivates youthful repair in old cells at the expense of long‑term survival, highlighting a trade‑off between rapid healing and stem cell longevity.

via ScienceDaily|

#aging #health-and-medicine #mtor

science1 month ago•5 min saved

Immunotherapy Sparks Hair Color Comeback, Hinting at Grey Hair Reversal

Emerging reports suggest grey hair might be reversible: cancer patients treated with immunotherapy drugs showed hair pigment returning, possibly by reactivating melanocyte stem cells. University of Alabama researchers are pursuing this for hair pigment, but no human trials exist yet, so practical applications are months away. Meanwhile, market supplements claim repigmentation with limited evidence.

via New York Post|

#greying-hair #hair-pigment #immunotherapy

sciencehealth1 month ago•5 min saved

Aging reveals a new fat-making stem cell driving belly fat growth

City of Hope and UCLA researchers identify a middle-age–specific stem cell population called committed preadipocytes (CP-As) that arise from adipocyte progenitor cells and markedly generate new fat cells in the belly; the process is driven by LIFR signaling, with mouse experiments showing aged APCs produce many new fat cells, and similar CP-A–like cells found in human tissue, suggesting a potential target to curb age-related belly fat.

via ScienceDaily|

#adipose-tissue #aging #belly-fat

health2 months ago•413 min saved

Immunotherapy Could Repaint Gray Hair, Early Research Finds

New research suggests immunotherapy drugs that activate the immune system might reactivate pigment-producing stem cells in hair follicles to restore color and possibly reverse graying, inspired by reports that some cancer patients treated with immunotherapy experienced hair repigmentation; current evidence comes from cells and animal models, with no approved gray-hair reversal yet. More human studies are needed—if gray hair is a medical concern, consult a dermatologist.

via TODAY.com|

#gray-hair #hair-pigmentation #health

science2 months ago•3 min saved

Electric Pulses Trigger Rejuvenation in Sea Squirts, Hinting at Human Anti-Aging Possibilities

Researchers delivered brief pacemaker-like electrical pulses to sea squirts, triggering an exercise-like surge in metabolism that improved stem cell activity, tissue growth, and even lifespan, with gene expression patterns resembling post-exercise responses; while promising, the findings are in a simple organism and their relevance to humans remains to be tested.

via bgr.com|

#aging #electric-stimulation #gene-expression

science2 months ago•4 min saved

Period Blood Emerges as a Promising Medical Resource

New studies show menstrual fluid speeds skin wound healing, may enable noninvasive cervical cancer screening with high sensitivity, can help detect endometriosis with a simple test strip, and contains stem cells with regenerative potential for infertility and neurological conditions, suggesting period blood could become a valuable biomedical resource rather than waste.

via Upworthy|

#diagnostics #endometriosis #menstrual-blood

science2 months ago•2 min saved

ISS Bioreactor Study Aims to Scale Up Stem Cell Therapies in Space

Astronauts on the International Space Station are testing a microgravity bioreactor (InSPA-StemCellEX-H2) to expand hematopoietic (blood-forming) stem cells in space, aiming to produce large quantities for Earth-based cancer and immune-disease therapies, potentially improving cell quality and reducing rejection compared with Earth-grown cells.

via NASA (.gov)|

#bioreactor #hematopoietic-stem-cells #iss

space3 months ago•13 min saved

Orbital Blastoids Probe Early Human Development in Microgravity

China sent stem-cell–derived embryo models (blastoids) to the Tiangong space station to study how the earliest stages of human development behave in microgravity. The experiment includes peri-implantation and peri-gastrulation models cultured for five days and then frozen for Earth-based analysis, with a ground-control batch for comparison. While it cannot prove humans can reproduce in space—blastoids are not real embryos and five days is a small window—it will provide concrete data on whether early development can tolerate off-Earth conditions and guide future research and engineering needs.

via Space Daily|

#biology #embryology #microgravity

space3 months ago•59 min saved

China Sends Lab-Grown Embryos to Space to Study Early Development in Orbit

China’s Tianzhou‑10 cargo mission delivered roughly 7 tons of supplies to the Tiangong space station and carried two types of living stem‑cell–based “artificial embryos” to study early human development in microgravity. Representing 14–21 days after fertilization, the peri‑implantation and peri‑gastrulation embryos will be grown for about five days in orbit, then frozen and returned to Earth for analysis to assess how space radiation and zero gravity affect embryo development—an important step for potential off‑Earth reproduction—though the researchers emphasize these are embryo‑like and not viable human embryos.

via Live Science|

#biology #china #embryology