estrogen-only therapy linked to lower dementia signals in menopause women

TL;DR Summary
A retrospective analysis across two datasets (21,462 records, including nearly 3,000 brain donors) found that estrogen-only hormone therapy for menopause was associated with fewer memory problems and lower Alzheimer’s biomarkers in brains. The study shows association, not causation, and could be influenced by confounding factors or missing data (e.g., hysterectomy status); more long-term randomized trials are needed to determine any protective effect.
- Estrogen-only hormone therapy could lower risk of Alzheimer’s Scientific American
- Study ties estrogen-based menopausal hormone therapy to lower Alzheimer’s risk Stanford Medicine
- Estrogen therapy is linked to fewer signs of Alzheimer’s in the brain Science News
- HRT drugs could slash risk of dementia in women, new study shows independent.co.uk
- Later-life estrogen therapy associated with lower risk of developing dementia News-Medical
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