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23andme

All articles tagged with #23andme

St. Louis man discovers Doobie Brothers singer Michael McDonald is his biological father
entertainment8 days ago

St. Louis man discovers Doobie Brothers singer Michael McDonald is his biological father

Michael Goessling, a 59-year-old St. Louis resident, recently confirmed that his biological father is five-time Grammy winner Michael McDonald. The revelation followed a 2025 letter from his birth mother’s attorney, prompted by a DNA test taken by McDonald’s son. Goessling, who had attended two of McDonald’s concerts unknowingly, described the discovery as a 'tsunami' but emphasized gratitude for his adoptive upbringing.

Rare EGFR Mutation Linked to 62-Fold Lung Cancer Risk in Never-Smokers
health15 days ago

Rare EGFR Mutation Linked to 62-Fold Lung Cancer Risk in Never-Smokers

A new study in Science identifies a rare inherited EGFR T790M mutation that dramatically increases lung cancer risk, particularly among never-smokers. Researchers found that carriers face 62 times the odds of developing the disease compared to non-carriers who have never smoked, and 25 times the odds overall. The mutation is rare nationwide but significantly more prevalent in Southern Appalachia due to a historical founder effect. While the study does not prove that genetic testing improves outcomes, it suggests future screening could be based on inherited risk rather than just smoking history.

Rare Genetic Mutation Identified as Major Lung Cancer Risk Factor for Non-Smokers
health16 days ago

Rare Genetic Mutation Identified as Major Lung Cancer Risk Factor for Non-Smokers

A rare inherited mutation in the EGFR gene, known as T790M, has been identified as a significant risk factor for lung cancer, particularly among non-smokers. A large-scale study involving over 3.3 million individuals found that carriers of this mutation have a 62-fold higher risk of developing lung cancer if they have never smoked, and a 25-fold higher risk overall. The mutation is rare, affecting approximately 1 in 15,850 people, and is most prevalent in populations with Southern Appalachian ancestry. Researchers suggest that genetic testing could lead to earlier screening and detection for at-risk individuals.

Inherited EGFR mutation sharply elevates lung cancer risk in nonsmokers
health22 days ago

Inherited EGFR mutation sharply elevates lung cancer risk in nonsmokers

A large study using 23andMe and other genetic data identified a rare inherited EGFR T790M mutation that dramatically increases lung-cancer risk, even in nonsmokers. Nonsmokers carrying the mutation have about 62-times higher odds of developing lung cancer than noncarriers, while the overallMutation carriers have roughly 25-times higher odds across smokers and nonsmokers; the mutation is very rare (about 1 in 15,850 people). It is more common in the U.S. Southeast (Alabama, Mississippi, Tennessee), which may help explain regional cancer disparities. The findings suggest genetic testing for people with a family history and earlier CT-based screening for carriers, with a clinical trial underway to assess screening timing and effectiveness.

Court orders $46.75M payout to 23andMe breach victims
business3 months ago

Court orders $46.75M payout to 23andMe breach victims

A California bankruptcy judge ordered Chrome Holding (operating as TTAM Research Institute) to pay about $46.75 million to victims of the 2023 23andMe data breach. Kroll Restructuring will distribute the funds to those affected, including users whose genetic data and relatives’ profiles were exposed, as 23andMe continues operating after bankruptcy and faces prior regulatory actions.

California Sues 23andMe Over 2023 Genetic Data Breach
technology4 months ago

California Sues 23andMe Over 2023 Genetic Data Breach

California Attorney General Rob Bonta says he will sue Chrome Holding (the post-bankruptcy rebrand of 23andMe) over a 2023 data breach that exposed genetic data for nearly seven million users and their relatives, alleging the company failed to protect data and misled consumers about the breach's severity. Investigators say the data was later sold on the dark web, and attackers used credential stuffing to access accounts, with reports that the breach involved targeting Asian American, Pacific Islander, and Jewish users.

Genes help explain why obesity drugs work differently for people
health6 months ago

Genes help explain why obesity drugs work differently for people

Nature reports a study of nearly 28,000 23andMe users who used obesity drugs, linking a GLP-1 receptor gene variant to greater weight loss (about 0.76 kg per copy, ~1.5 kg for two copies) over a median of 8 months, and other variants to higher risk of side effects like nausea. Overall genetic effects on weight loss are modest, but associations with adverse effects are stronger; findings come from self-reported data and are not yet ready to guide clinical practice.

Court Approves 23andMe Sale to Founder-Led Nonprofit
business1 year ago

Court Approves 23andMe Sale to Founder-Led Nonprofit

Anne Wojcicki's nonprofit TTAM Research Institute has received court approval to purchase 23andMe's assets for $305 million, ending a bidding war and marking the company's exit from bankruptcy. The deal includes the company's DNA testing services, research operations, and a telehealth subsidiary, with commitments to data privacy and customer protections. The acquisition's future leadership and regulatory challenges remain uncertain.

23andMe sale to founder-led nonprofit approved amid legal and regulatory challenges
business1 year ago

23andMe sale to founder-led nonprofit approved amid legal and regulatory challenges

Anne Wojcicki's nonprofit TTAM Research Institute has been approved to buy back 23andMe for $305 million after the company's bankruptcy, marking a significant turnaround. The deal includes key assets like the DNA testing service and research operations, amid ongoing privacy concerns and legal challenges related to customer data. Wojcicki aims to continue the company's mission to democratize access to genetic information, with commitments to privacy and transparency.

UK fines 23andMe £2.3m for data breach
business1 year ago

UK fines 23andMe £2.3m for data breach

23andMe was fined £2.31 million by the UK ICO for a significant data breach in 2023 that exposed sensitive personal information of thousands, including UK residents, due to inadequate security measures. The breach involved credential stuffing attacks, and the company failed to implement proper authentication protocols. Now in bankruptcy, 23andMe is being sold to TTAM Research Institute, which commits to enhancing data protections and consumer rights.

Anne Wojcicki's Nonprofit Wins Bid to Reclaim 23andMe
business1 year ago

Anne Wojcicki's Nonprofit Wins Bid to Reclaim 23andMe

Anne Wojcicki, former CEO of 23andMe, regained control of the genetic testing company by bidding $305 million at auction, outbidding Regeneron Pharmaceuticals, after the company filed for bankruptcy due to declining demand and a data breach. The sale has sparked legal challenges from multiple states over privacy concerns, with a court hearing scheduled to determine the company's future.