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Anelloviridae

All articles tagged with #anelloviridae

health1 month ago•6 min saved

Dormant viruses awaken during COVID-19, potentially driving severity and long COVID

A study of 1,150 hospitalized COVID-19 patients found reactivation of dormant viruses from the Herpesviridae and Anelloviridae families in about 48% of cases, with HSV1 and CMV reactivating around day 20 and detection in nasal or blood samples linked to greater disease severity and higher 1-year mortality. Notably, Anelloviridae reactivation months after illness was associated with fatigue and disability (long COVID). The study shows association, not causation, and involved unvaccinated patients with early SARS-CoV-2 strains, so more research is needed to understand implications for prognosis and treatment."

via Medical News Today|

#anelloviridae #covid-19 #health

science1 month ago•48 min saved

Severe COVID-19 May Unleash Dormant Viruses, Study Finds

A multi-center study of 1,154 hospitalized COVID-19 patients over a year found reactivation of 11 dormant viruses within the first 40 days of admission, including Epstein-Barr virus, cytomegalovirus, herpes simplex virus-1, and Anelloviridae. Reactivation appeared linked to inflammation rather than immune suppression and was also associated with long-COVID and long-term disability in some cases, though causation was not established. The findings shed light on how severe COVID-19 can impact the body’s virome and may inform future diagnostics and treatments, especially for those with severe disease.

via Yahoo|

#anelloviridae #covid-19 #cytomegalovirus

health2 months ago•3 min saved

Dormant viruses wake in severe COVID-19 patients, new study suggests

A large multi-center study of 1,154 hospitalized COVID-19 patients found 11 dormant viruses reactivated within 40 days of admission, including Epstein-Barr, cytomegalovirus, herpes simplex virus-1 and Anelloviridae; Anelloviridae reactivation was linked to long COVID and disability, while EBV/CMV reactivation appeared tied to inflammation rather than immune suppression. The study does not prove causation but may help explain long COVID and guide future diagnostics and therapies, though results apply to severe cases only.

via ABC News - Breaking News, Latest News and Videos|

#anelloviridae #covid-19 #health

health2 months ago•8 min saved

Dormant viruses reawaken in severe COVID, fueling long COVID and autoimmune risks

Nature study of 1,154 hospitalized COVID-19 patients shows severe illness can reactivate dormant viruses (11 viruses detected within 40 days), notably Anelloviridae linked to long COVID, while EBV and CMV reactivation in nasal/blood samples correlate with higher mortality and complications; findings suggest viral reactivation monitoring could help prognosticate and treat acute and long COVID, though causality isn’t proven and more research is planned.

via CIDRAP|

#anelloviridae #autoimmune-disease #covid-19

science2 months ago•89 min saved

Chronic Virus Reactivation Linked to Severity and Long COVID in COVID-19 Patients

A large, longitudinal study of 1,154 hospitalized COVID-19 patients using multi-omic analyses found significant reactivation of chronic viruses, especially Herpesviridae (EBV, CMV, HSV) and Anelloviridae, during acute illness with distinct timing for different viruses. Reactivation correlated with greater disease severity and adverse outcomes and persisted into convalescence, with Anelloviridae associated with long COVID. Although causality isn’t established, the results show frequent viral reactivation in immunocompetent patients during severe illness and reveal immune, transcriptomic, and metabolic changes linked to reactivation, offering potential prognostic and therapeutic insights for acute COVID-19 and long COVID.

via Nature|

#anelloviridae #herpesviridae #long-covid