Tag

Immune System

All articles tagged with #immune system

health4 days ago•6 min saved

Tiny immune signals and daily habits: a practical path to healthier aging beyond 100

A small Osaka University study suggests centenarians have a higher share of rare CD4 cytotoxic T lymphocytes, hinting at an immune edge in extreme aging, though the finding is preliminary. The article also outlines practical habits linked to healthier aging: regular movement, a varied nutrient-rich diet, sufficient sleep, mental stimulation, social connections, stress management, and preventive healthcare. While these steps don’t guarantee reaching 100, they can boost energy, independence, and the number of healthy years.

via The Times of India|

#aging #centenarians #health

science6 days ago•5 min saved

Centenarians Harbor More CD4 Cytotoxic T Cells, Study Finds

New findings published in Cell Reports show that supercentenarians tend to have a higher proportion of CD4 cytotoxic T cells, a rare killer T cell type that expands and clones with age, suggesting the aging immune system adapts to threats and may help protect against cancer in extreme old age, though the study is small and Japan-based.

via ScienceAlert|

#aging #cd4-cytotoxic-t-cells #centenarians

science9 days ago•5 min saved

Aging Blood Stem Cells May Spark Inflammation Across the Body

New mouse studies show aging blood stem cells can drive inflammation in distant tissues by producing inflammatory immune cells. Boosting SIRT3 in these cells reduced inflammatory outputs and improved mobility, metabolic control, and lung health; transferring these immune cells to other mice conveyed similar benefits. Findings are preliminary and in animals, so it’s not yet clear if humans share the mechanism or if SIRT3 could be a therapeutic target for aging.

via sciencealert.com|

#aging #immune-system #inflammation

health12 days ago•57 min saved

Gut-Immune Link Might Explain Why You Feel 'Always Sick'

An immunologist says feeling like you’re “always sick” is deeply personal and may reflect an immune system that’s constantly challenged. He emphasizes starting with gut health, noting that the gut microbiome trains the immune system and that shifts in gut bacteria can influence how the body responds to infections. Improving gut health—through quality sleep, plenty of dietary fiber, probiotics, and mindful antibiotic use—may help reduce sickness frequency, though stress, diet, and rare hereditary factors can also play a role. Always discuss persistent illness with your healthcare provider.

via AOL.com|

#fiber-probiotics #gut-health #gut-microbiome

science16 days ago•7 min saved

A Week of Intensive Meditation Rewires Brain and Body

A seven-day meditation retreat in healthy adults produced broad brain, metabolic, immune, and pain-regulation changes, with brain activity showing reduced internal mental chatter, evidence of increased neuroplasticity, altered metabolism, higher endogenous opioid levels, and shifts in immune signaling; brain connectivity patterns resembled those seen with psychedelic states, though the study cannot separate which components caused the effects and further trials are needed to assess durability and clinical relevance.

via ScienceDaily|

#brain-connectivity #endogenous-opioids #immune-system

science17 days ago•9 min saved

Explosive defense: neutrophils deploy DNA nets to trap invaders

Neutrophils kill pathogens by self-destructing and releasing DNA-coated enzyme nets (NETs) that trap and destroy invaders. This NETosis process has three forms—suicidal, vital, and mitochondrial—and, while a rapid and effective defense, excessive NET formation can drive tissue damage in diseases such as lupus, small vessel vasculitis, sepsis, and severe COVID-19. First characterized in 2004 and now widely confirmed, NETosis is a powerful, double-edged weapon of the innate immune system.

via Space Daily|

#immune-system #inflammation #netosis

science22 days ago•4 min saved

Arginine Could Reinforce Immune Alarm Signals in Cancer and Viral Infections

Arginine deficiency weakens immune surveillance by lowering MHC-1 production, and a modest dietary boost could restore this immune signal. In cell culture and mouse studies of colon cancer and viral infections (influenza and SARS-CoV-2), higher arginine reduced tumors and improved outcomes, hinting that arginine supplementation might complement immunotherapies or help at-risk groups. Since arginine levels decline with age and poor nutrition, this could partly explain increased cancer and infection vulnerability.

via ScienceDaily|

#arginine #cancer #immune-system

science25 days ago•5 min saved

Untangling the Gluten-Driven Chain Reaction Behind Celiac Gut Damage

A comprehensive review of 100+ studies maps how genetic risk, the TG2 enzyme, immune cells (including intraepithelial lymphocytes), stromal cell signals, and gut bacteria interact to amplify gluten-triggered immune damage to the gut lining. This multi-factor cascade helps explain why only some genetically predisposed people develop celiac disease and could guide future therapies beyond a gluten-free diet.

via ScienceAlert|

#celiac-disease #gluten #gut-microbiota

health-and-medicine29 days ago•4 min saved

One Sauna Session Briefly Boosts Immune Cells in Blood

A 30-minute sauna session with a mid-way cold shower temporarily increases all circulating white blood cell types, including neutrophils and lymphocytes, peaking during heat exposure and returning to baseline about 30 minutes after the session ends. The rise likely reflects mobilization of immune cells from tissues—a mechanism similar to exercise that could enhance immune surveillance—though cytokine changes were small and long-term effects remain unknown. The study involved 51 adults and was published in Temperature, focusing on immediate, not lasting, immune responses.

via ScienceDaily|

#health-and-medicine #immune-system #lymphocytes

health1 month ago•10 min saved

Shingles Hits Millennial Women, Prompting Health Officials to Reassess Risk

Shingles, a reactivation of the chickenpox virus, is increasingly diagnosed in people in their 30s and 40s, with women disproportionately affected. The article follows Francine Jones, 39, and others who describe severe pain and a blistering rash, showing how younger adults can be missed or diagnosed late. Experts say antivirals work best within 72 hours, and rising cases in the US and UK are prompting discussion of causes—from stress and immune changes to shifts in vaccination dynamics—alongside calls for broader vaccination in high-risk groups and attention to overall health as prevention.

via The Guardian|

#health #immune-system #millennial

health1 month ago•5 min saved

The shrinking thymus: could aging's key lie in a hidden immune organ?

New research on the thymus—the immune gland that shrinks with age—suggests thymic health may influence longevity and cancer immunotherapy outcomes. Analyses of CT scans linked a robust thymus with longer life and lower disease risk, while thymus removal was associated with higher mortality and cancer risk in observational data, though causality isn’t proven. Scientists are exploring ways to slow or reverse thymic involution, with early work aiming at patients with unmet medical needs.

via Al Jazeera|

#aging #health #immune-system

science1 month ago•5 min saved

Gentle stem-cell transplant hints at rejuvenating aging blood and immunity in mice

A study in mice shows that transplanting young, lab-expanded blood-forming stem cells into aged animals—without chemotherapy or radiation—restores blood production and rebirths of immune cells (naive B and T cells), effectively reshaping the aging immune system. While the approach worked in mice and used a gentler method (including targeted helpers to spare healthy cells), it is far from clinical use in humans and faces safety, regulatory, and scalability hurdles; nonetheless, experts see potential for future therapies that renew the body’s blood-forming system rather than wide-ranging anti-aging cures.

via SciTechDaily|

#aging #immune-system #regenerative-medicine

science1 month ago•5 min saved

New Death Footprint Reveals How Viruses Hitch a Ride During Cell Cleanup

Researchers have identified a novel death-derived extracellular vesicle type, F-ApoEVs, that guides the immune system’s cleanup after apoptosis. These 'footprints of death' can be exploited by viruses (e.g., influenza) to hitch a ride to neighboring cells, revealing a new route for viral spread. The Nature Communications study suggests these footprints could be targeted to bolster immune clearance and combat autoimmune diseases, though further research is needed.

via ScienceAlert|

#apoptosis #extracellular-vesicles #f-apoevs

entertainment1 month ago•49 min saved

Sam Neill’s Final Battle: Cancer, Pneumonia and a Compromised Immune System

Jurassic Park star Sam Neill died at 78 after a years-long cancer fight. His ex, Australian journalist Laura Tingle, said his immune system was compromised by chemotherapy and immunotherapy, and that he’d been pretty sick in the weeks before his death. Neill had battled a form of blood cancer since 2022 and was reportedly cancer-free as of April, with pneumonia cited by friends as a factor in his final days.

via Yahoo|

#cancer #entertainment #immune-system

science1 month ago•9 min saved

Thymus revival: a race to reboot aging immune system

Researchers are racing to regrow the thymus, an immune organ that shrinks with age, after studies linked poorer thymic health with higher mortality and cancer risk. Startups and investors are funding thymus-regeneration programs and early trials are underway, but much of the evidence remains correlative, and it’s still unclear whether reviving the thymus can truly slow aging or reduce cancer risk.

via Nature|

#aging #immune-system #longevity