Mayo Clinic Trial Shows High-Dose Probiotic Reduces Bile Acids in Chronic Diarrhea
A small randomized trial at Mayo Clinic found that a high-dose, eight-strain probiotic reduced fecal primary bile acids in patients with bile acid malabsorption. While the treatment improved biochemical markers and altered gut microbiome composition, it did not significantly change stool consistency or frequency. The authors note the study's small sample size and short duration limit its conclusions, calling for larger, longer trials to confirm therapeutic benefits.
