Tag

Gut Microbiome

All articles tagged with #gut microbiome

health6 days ago•18 min saved

Experts warn rapid fiber increases disrupt gut health, urging gradual dietary shifts

Recent coverage highlights the complexity of maintaining a healthy gut microbiome, emphasizing that rapid dietary changes, such as the 'fibermaxxing' trend, can cause digestive distress. While whole foods like beans and Greek yogurt are recommended for their fiber and probiotic content, experts caution that the gut requires gradual adaptation to new fiber levels. Research indicates that a stable microbiome is crucial for immune function and disease prevention, with early-life exposures playing a significant role in long-term health outcomes.

via The Independent|

#dietary-health #fiber-intake #gut-microbiome

science8 days ago•3 min saved

Microgravity slows gut transit, shifting bacteria to protein fermentation and causing constipation

A University of Copenhagen and NASA study found that microgravity slows intestinal movement, causing gut bacteria to ferment protein instead of fiber. This shift, detected in blood samples from 52 ISS astronauts, explains common space constipation and poses risks for long-duration missions to Mars.

via ScienceDaily|

#gastroenterology #gut-microbiome #microgravity

health9 days ago•39 min saved

Mayo Clinic Study Links Distinct Gut Microbiome Signatures to Five Cancer Types and Early-Onset Disease

Mayo Clinic researchers published a study in Cell analyzing stool samples from 1,364 cancer patients, identifying 341 bacterial species linked to five specific cancer groups. The study found distinct microbiome patterns in adults under 50 with colorectal and breast cancer, including higher lactate levels and specific bacteria like Veillonella parvula. Additionally, pre-treatment gut bacteria levels predicted chemotherapy-induced diarrhea, specifically for 5-fluorouracil, offering a potential biomarker for treatment side effects.

via Newsweek|

#cancer-research #cell-journal #chemotherapy-side-effects

health9 days ago•212 min saved

Sugar intake during antibiotic use accelerates gut microbiome collapse, study finds

A new study in Nature reveals that consuming sugary foods while taking antibiotics significantly worsens gut microbiome disruption. Researchers found that sugar intake during antibiotic treatment led to a 24% drop in bacterial diversity for every 100-gram increase in sweets, promoting the overgrowth of harmful Enterococcus bacteria. This effect was confirmed in mouse models, where sugar supplementation increased Enterococcus populations by up to 33-fold. The findings suggest that limiting sugar during antibiotic courses could protect gut health and improve clinical outcomes, particularly for cancer patients undergoing stem cell transplants.

via CNN|

#antibiotics #cancer-care #enterococcus

health-and-science9 days ago•86 min saved

Study Links Sugar Intake to Worsened Gut Microbiome Damage During Antibiotic Treatment

A new study in Nature finds that consuming sugar-rich foods while taking antibiotics worsens gut microbiome disruption. Researchers tracked 9,419 meals from 173 patients undergoing hematopoietic cell transplantation, finding that sugar intake during antibiotic exposure led to lower microbial diversity and increased growth of the pathobiont Enterococcus. Mouse experiments confirmed that sucrose supplementation prolonged this bacterial expansion. The findings suggest that avoiding simple sugars during antibiotic treatment could help mitigate microbiota damage and improve recovery.

via nature.com|

#antibiotics #clinical-trials #enterococcus

science-and-health10 days ago•1 min saved

Coffee's Gut-Brain Link: New Studies Reveal How Brews Reshape Microbiome and Mood

Recent research indicates that coffee influences the gut microbiome more than 150 other foods, potentially affecting mood and cognition through the gut-brain axis. While caffeinated coffee reduces anxiety, decaf may improve memory, suggesting benefits extend beyond caffeine.

via BBC Science Focus Magazine|

#brain-health #coffee #decaf-benefits

science19 days ago•79 min saved

Early-life gut microbiome trajectories plus genetics predict type 1 diabetes risk

A TEDDY cohort study of 887 children followed for up to 6 years identifies three gut microbiome maturation patterns (Early Matured, Late Matured, Early Plateaued) driven mainly by Bifidobacterium and Ruminococcus. The Early Plateaued pattern associates with a threefold higher risk of type 1 diabetes, while host genetic variants related to immune responses modify the linkage between the Late Matured pattern and diabetes risk, indicating that early microbial exposures and genetics together shape T1D susceptibility.

via Nature|

#early-life-development #gut-microbiome #host-genetics

health21 days ago•4 min saved

Two Daily Foods, One Big Limit: A Dietitian's Plan to Cut Colorectal Cancer Risk

Colorectal dietitian Sophie Medlin advocates two daily habits—eat diverse plant foods and daily fermented foods—while limiting red meat to two portions per week and avoiding processed meat, to help lower colorectal cancer risk as cases rise among younger adults and gut health is linked to cancer prevention.

via businessinsider.com|

#colon-cancer #diet #fermented-foods

health22 days ago•4 min saved

High-Dose Eight-Strain Probiotic Improves Biochemical Markers in Bile Acid Malabsorption

In a small randomized Mayo Clinic trial, adults with bile acid malabsorption and chronic diarrhea who received a high-dose eight-strain probiotic (900 billion CFU twice daily for 21 days) showed a reduction in the percentage of fecal primary bile acids—driven mainly by lower chenodeoxycholic acid—and shifts in gut microbiome composition, compared with placebo. There were no consistent changes in stool frequency/consistency, serum 7-alpha-C4, or intestinal permeability. The probiotic was well tolerated, but the sample size was small and longer, larger studies are needed to confirm clinical benefits.

via Medscape|

#bile-acid-malabsorption #gut-microbiome #health

health-and-medicine23 days ago•5 min saved

Kimchi-Derived Probiotic Boosts Nanoplastics Excretion

A kimchi-derived lactic acid bacterium, Leuconosteroides mesenteroides CBA3656, binds nanoplastics in gut-like conditions and maintains substantial adsorption under simulated intestinal conditions, leading to a >2× increase in fecal nanoplastics in germ-free mice and suggesting a potential microbial approach to reduce nanoplastic accumulation by promoting excretion.

via ScienceDaily|

#adsorption #gut-microbiome #health-and-medicine

science1 month ago•4 min saved

Gut Fungus Could Shield the Body from Radiation, Study Finds

A PNAS study shows the gut-dwelling fungus Mucor racemosus can reduce radiation-related damage in mice by producing protective amino acids (L-glutamic acid, L-aspartic acid, DL-lysine) and by MTA-mediated changes in gut bacteria that raise methionine. The radioprotective effect persists in germ-free mice and is enhanced when the fungus is preadapted to the gut’s low-oxygen environment; feeding irradiated mice cheese fermented with the fungus also reduced inflammation and improved gut barriers. While promising, more research is needed before humans can rely on this, and immunocompromised individuals should be cautious—even though the fungus occurs in some fermented foods and is FDA-approved for dietary use.

via ScienceAlert|

#gut-microbiome #methylthioadenosine #mucor-racemosus

health1 month ago•206 min saved

Wearable fart tracker aims to map gut health

Researchers from the University of Maryland have created a smart underwear device with a hydrogen-detecting disc to measure flatulence as part of the Human Flatus Atlas. By collecting fart data alongside meals, scientists hope to understand how the gut microbiome responds to different foods—especially fiber—and how this relates to digestive comfort and health. Early studies reported about 32 farts in a 12-hour window, and a larger follow-up with 500+ volunteers wearing the device for 3–30 days is underway, aiming to pave the way for noninvasive gut-health insights and potential future diagnostics (though not a medical device yet).

via CNN|

#digestive-health #gut-microbiome #health

health1 month ago•4 min saved

Systemic antifungal therapy reshapes the gut microbiome in some IBD patients

A Nature Medicine study from Weill Cornell compared two weeks of fluconazole (systemic) vs nystatin (mouthwash) in 53 IBD patients with oral thrush. Fluconazole reduced intestinal Candida, remodeled gut fungal and bacterial communities, increased bacterial diversity and butyrate production, and was associated with lower disease activity and slower progression over eight weeks, unlike nystatin. The trial was not randomized or placebo-controlled, so findings are preliminary and justify a larger multicenter trial to confirm efficacy and explore broader patient applicability.

via news.cornell.edu|

#antifungal-therapy #candida-albicans #fluconazole

health1 month ago•31 min saved

Fluconazole reshapes the gut microbiome and improves disease activity in IBD

In a prospective study of 53 patients with mild-to-moderate inflammatory bowel disease (UC or Crohn’s), fluconazole reduced gut Candida burden and reshaped the fungal community, triggering cross-kingdom shifts that increased bacterial diversity and boosted butyrate-producer and anti-inflammatory metabolites, correlating with improved disease activity over 8 weeks; oral nystatin did not have these effects, suggesting mycobiome-targeted antifungal therapy may help IBD management.

via Nature|

#antifungal-therapy #candida-albicans #fungal-microbiome

health1 month ago•6 min saved

Intestinal Fructose Processing May Boost Fat Absorption and Obesity, Mouse Study Finds

UC Irvine researchers found that blocking the small intestine’s fructose-processing enzyme (KHK-C) in mice fed high-fructose corn syrup reduced weight gain and fat mass, altered the gut microbiome, and shortened lacteals to lower fat absorption; fecal transplants from these mice caused similar fat-absorption effects, suggesting intestinal fructose metabolism helps drive fat uptake and obesity, though human studies are needed.

via ScienceAlert|

#fat-absorption #fructose #gut-microbiome