Tag

Gut Microbiome

All articles tagged with #gut microbiome

health4 days ago•1 min saved

Sweeteners May Have Hidden Metabolic Costs, New Analysis Finds

A review of 21 randomized trials links artificial and low-calorie sweeteners to higher fasting insulin and HbA1c, with a possible reduction in insulin sensitivity; gut microbiome changes may be involved, and higher consumption could relate to greater cardiometabolic risk, though causality isn’t proven. While avoiding large amounts of added sugar is prudent, replacing sugar with these sweeteners may be better than sugar, but not risk-free.

via U.S. News & World Report|

#artificial-sweeteners #gut-microbiome #hba1c

science4 days ago•5 min saved

Gut Bacterium May Help Preserve Muscle Strength With Age

A gut bacterium, Roseburia inulinivorans, is linked to stronger muscles and better fitness, with levels declining as people age. In humans, older adults with detectable R. inulinivorans had about 29% higher grip strength; in mice, supplementation boosted forelimb grip strength by ~30% and increased the proportion of fast-twitch (type II) muscle fibers, suggesting a gut–muscle axis and probiotic potential for sarcopenia. The study also notes species-specific effects and limitations, including that colonization did not occur in the mouse model and long-term human trials are needed to confirm causality and benefit.

via SciTechDaily|

#gut-microbiome #muscle-strength #probiotic

science6 days ago•12 min saved

Gut-brain axis links aging memory; Stanford study reverses deficits in mice

Stanford researchers show age-related memory loss in mice can be driven by gut microbiome changes that weaken signals along the vagus nerve to the hippocampus; by modifying gut bacteria or stimulating the vagus nerve, old mice regained memory performance, suggesting peripheral gut-brain interventions could help human cognitive aging.

via SciTechDaily|

#aging #cognitive-decline #gut-microbiome

science8 days ago•5 min saved

Gut Bacterium Reverses Lupus Signs in Mice, Hinting at New Treatments

A UT Health San Antonio team found that supplementing the gut bacterium Faecalibacterium prausnitzii, depleted in lupus, reduced lupus biomarkers and protected organs in mouse lupus models. The bacterium improved fiber digestion, boosted anti-inflammatory cells, and normalized gut barriers, suggesting a potential probiotic approach for lupus. However, F. prausnitzii is oxygen-sensitive and not a lasting probiotic, so researchers will investigate how its metabolites interact with the immune system and how diet influences its levels before considering human applications. The study, published in Nature Communications, marks the first demonstration that restoring this bacterium can mitigate lupus-related dysfunction in animals.

via ScienceAlert|

#faecalibacterium-prausnitzii #gut-microbiome #immunology

health11 days ago•4 min saved

Gut microbiome clues point to earlier colorectal cancer detection

A large study identifies a consistent gut microbiome signature in stool that tracks with colorectal tumors across ages, suggesting potential for earlier detection. The cancer-associated microbiome is stronger with low dietary fiber and weaker with higher fiber, while ultra-processed foods are linked to rising colorectal cancer in younger adults. Researchers caution this is not yet a diagnostic test, but it advances understanding of microbiome-disease links and prevention prospects.

via New York Post|

#colorectal-cancer #diet #early-detection

science15 days ago•72 min saved

Blood metabolome links midlife brain health to genes, gut microbiome, and exposures

In 1,082 dementia-free midlife participants, researchers linked 14 cognition-associated blood metabolites (ergothioneine strongest) and 22 metabolites with MRI brain markers. The metabolite patterns mirrored the signature of incident AD across replication cohorts. Genetic variation, gut microbiota, lifestyle, clinical factors, and medications all shaped metabolite levels, with lifestyle and clinical factors being particularly influential; antacid use correlated with worse cognition and lower ergothioneine, which mediated about 31.5% of this effect. The cognition and AD-risk metabolite signatures overlap, suggesting prevention avenues via modifiable exposures and gut microbiome factors.

via Nature|

#alzheimers-disease #cognition #exposome

health16 days ago•7 min saved

Fermented Foods Offer Subtle Health Clues, Not Definitive Answers

Fermented foods like yogurt, kimchi and sauerkraut may modestly improve gut microbes and inflammatory markers, but current evidence is limited and mostly observational; potential benefits include lower eczema risk and better metabolic markers, yet findings aren’t causal and results vary; considerations include histamines, high sodium, and caution for immunocompromised individuals; more robust research is needed.

via The New York Times|

#fermented-foods #gut-microbiome #health

health-and-training21 days ago•14 min saved

Brewing Brain and Belly: Coffee Rewires Your Gut for Better Mood and Performance

A University College Cork study shows coffee reshapes the gut microbiome and gut-brain axis, with certain bacteria thriving in coffee drinkers; decaf improves memory, sleep, and mood, while caffeinated coffee enhances attention and lowers inflammation, indicating coffee’s benefits go beyond caffeine and may affect mood, recovery, and cognitive function—useful insights for athletes, though individual microbiomes vary.

via Škoda We Love Cycling|

#caffeine #coffee #cognition

science21 days ago•6 min saved

Sugar-Free Diet in Mice Triggers Hidden Metabolic Setbacks

A 16-week mouse study found that removing sucrose from a low-fat diet disrupted gut bacteria, reduced beneficial microbes, and led to metabolic problems—impaired glucose control, insulin resistance, and fat buildup in the liver—despite similar body weight. The researchers caution that the findings, presented at ENDO 2026 and awaiting peer review, don’t yet translate to humans and suggest that completely eliminating sugar may not always be beneficial, underscoring the need to balance carbohydrates and gut health.

via ScienceAlert|

#gut-microbiome #insulin-resistance #metabolic-health

health22 days ago•10 min saved

Extreme sugar-cutting may backfire on gut health, new study finds

A mouse study suggests zero-sugar diets can impair metabolic health by disrupting the gut microbiome and breaking down the gut barrier, even when the animals stay slim. Given the tiny sample size and the strictly low-fat diet used, human relevance is uncertain, but the research cautions against extreme elimination diets and advocates a balanced approach that supports gut diversity with a variety of fruits, vegetables, grains and fermented foods, while avoiding highly processed sugars.

via The Conversation|

#clean-eating #gut-microbiome #health

health23 days ago•6 min saved

Removing all sugar may backfire on gut health, mouse study finds

A 16-week mouse study comparing a low-fat diet with and without sucrose found that eliminating sugar disrupted gut bacteria, increased intestinal and liver inflammation, and worsened glucose regulation and insulin sensitivity, even without weight gain. The results suggest that total sugar bans may have unintended gut and metabolic consequences in humans, though further trials are needed.

via Fox News|

#fatty-liver #gut-microbiome #health

health24 days ago•7 min saved

Tiny Ferments, Big Gut Payoff: Easy Ways to Eat More Fermented Foods

Fermented foods—yogurt, kimchi, sauerkraut, kefir and more—support gut health by delivering probiotics and fermentation-derived nutrients, potentially lowering inflammation and improving blood sugar while boosting gut microbiome diversity; aim for 1–2 servings daily with a variety of types, watch sodium in some choices, and consult a doctor if you’re immunocompromised.

via The Washington Post|

#fermented-foods #gut-microbiome #health

health-and-medicine25 days ago•6 min saved

117-Year-Old's Gut Microbiome Hints at a Youthful Core

Researchers studying María Branyas Morera, who died at 117, found her gut microbiome was dominated by Bifidobacterium (about half the community), a profile more typical of infants, and DNA methylation clocks suggested her biological age was 17–23 years younger than her actual age; the study, led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute, indicates gut health likely plays a role in aging but cautions that no single habit—like yogurt or diet—explains extreme longevity, which also depends on genetics and lifestyle.

via Sacramento Bee|

#aging #bifidobacterium #dna-methylation

health26 days ago•5 min saved

Going Sugar-Free May Disrupt Gut Health, Mice Show Metabolic Struggles

A mouse study presented at ENDO 2026 found that removing sucrose from a low-fat diet did not improve metabolic health but disrupted the gut microbiome, caused intestinal and liver inflammation, and worsened glucose tolerance and insulin resistance, despite similar weight to controls, suggesting that completely eliminating sugar may be counterproductive and that balanced carbohydrate intake supports gut and metabolic health.

via SciTechDaily|

#balanced-diet #fatty-liver-disease #gut-microbiome

health-and-medicine26 days ago•5 min saved

Eliminating sugar may backfire on gut health and metabolism

A study presented at ENDO 2026 found that removing sucrose from a low-fat diet in mice worsened glucose control, increased inflammation, disrupted gut microbiota, and showed signs of fatty liver, suggesting that balanced carbohydrate intake supports gut and metabolic health rather than complete sugar elimination.

via ScienceDaily|

#fatty-liver #gut-microbiome #health-and-medicine