Tag

Gut Microbiome

All articles tagged with #gut microbiome

health56 minutes ago•63 min saved

Gut microbes could be quietly steering what you crave

New evidence suggests gut bacteria may influence what we crave. In mice, transferring different microbiomes altered protein vs. carbohydrate preferences, likely via serotonin production linked to tryptophan levels. A 2025 Nature Microbiology study also ties a gut bacterium to reduced sugar cravings through a GLP-1 pathway. Experts caution that human eating is shaped by culture and other factors, so more research is needed to confirm similar effects in people.

via Live Science|

#bidirectional-feedback #brain-gut-axis #cravings

health-and-medicine23 hours ago•6 min saved

AI-Driven Stool Test Detects 90% of Colorectal Cancers, Offering Non-Invasive Screening

Researchers at the University of Geneva used artificial intelligence to map gut microbiota subspecies and develop a stool-based test that identified about 90% of colorectal cancers, approaching colonoscopy’s 94% detection rate. If validated in ongoing trials, this non-invasive method could replace routine screening with colonoscopies reserved for positives, while expanding screening accessibility.

via ScienceDaily|

#colorectal-cancer #gut-microbiome #health-and-medicine

science1 day ago•8 min saved

Diet–Gut Signals Flip White Fat into Calorie-Burning Beige Fat in Mice

Researchers found that a low-protein diet activates a specific gut‑bacteria community that emits signals causing white fat to become beige, calorie‑burning fat in mice. Four bacterial strains are needed, and the effect relies on a two‑step process: changes in bile acids push fat cells toward burning energy, and the liver releases FGF21 to boost metabolism. The effect disappears if either signal is blocked, showing the microbiome’s diet‑interpreting role. While promising for metabolic disease targets, human applicability remains unproven and the diet used isn’t recommended for people; the work points to pathways for therapies that mimic these microbial signals rather than extreme diets or probiotics alone.

via SciTechDaily|

#beige-adipocytes #fat-browning #gut-microbiome

science1 day ago•5 min saved

Researchers uncover hidden gut virus tied to colorectal cancer

A Danish-led study identifies a previously unknown bacteriophage inside the gut bacterium Bacteroides fragilis that is more common in individuals with colorectal cancer, a pattern replicated in independent cohorts from Europe, the US, and Asia. While the virus–bacterium interaction may help explain cancer risk and could become a future stool-based screening marker, causality is not yet established, and researchers are pursuing further experiments in gut models, tumor tissue, and animal studies.

via SciTechDaily|

#bacteriophage #bacteroides-fragilis #colorectal-cancer

health-and-medicine2 days ago•6 min saved

Hidden gut sugars linked to ALS and dementia, opening new therapy paths

New research shows harmful sugars produced by gut bacteria trigger immune responses that damage brain cells in ALS and frontotemporal dementia; elevated levels were found in a majority of patients studied, and experiments reducing these sugars improved brain health and lifespan, pointing to gut-targeted therapies and biomarkers to slow disease progression—especially in carriers of the C9orf72 mutation.

via ScienceDaily|

#als #frontotemporal-dementia #glycogen

science2 days ago•37 min saved

Pantry staples could blunt cholera infection, study finds

UC Riverside researchers report that a high-protein diet rich in casein and wheat gluten dramatically lowers cholera bacteria in the gut—up to 100-fold in infected mice—by interfering with the bacteria's toxin-delivery syringe; a promising food-based prevention strategy pending human studies, with potential to reduce antibiotic reliance, though the exact amounts and timing for humans remain unknown.

via Yahoo|

#casein #cholera #gut-microbiome

science11 days ago•9 min saved

Gut-Brain Signaling Reverses Age-Related Memory Decline in Mice

A Nature study shows aging gut microbiomes produce molecules that blunt gut-brain signaling via the vagus nerve, contributing to memory decline in mice. When older microbiomes were transferred to young mice, memory worsened, but antibiotics or a targeted phage against Parabacteroides_goldsteinii restored function. Direct vagus nerve stimulation through gut hormones also reversed memory deficits in old mice, suggesting that age-related memory loss may be driven by body-wide signals and could be reversible with existing or developing therapies, though human applicability remains to be determined.

via scitechdaily.com|

#aging #gut-microbiome #memory-loss

mental-health11 days ago•26 min saved

Glyphosate exposure may spark anxiety by reshaping gut microbes

A 16-week study in adult male rats shows daily exposure to the government-safe glyphosate dose (2 mg/kg) alters gut bacteria—reducing Lactobacillus—and elevates anxiety-like behavior, including avoidance of open spaces and novel objects, with increased activity in the bed nucleus of the stria terminalis; findings suggest regulatory safety limits on glyphosate may underestimate neurobehavioral risks.

via PsyPost|

#anxiety #bed-nucleus-of-the-stria-terminalis #glyphosate

health14 days ago•69 min saved

New gut microbe from Mediterranean diet shown to boost mouse strength

Researchers find that a Mediterranean-diet–associated gut bacterium, Roseburia inulinivorans, correlates with higher grip strength in humans and, when fed to mice, increases grip strength by about 30% over 4–8 weeks and shifts muscle fibers toward a stronger, fast-twitch type. The study suggests potential probiotic or drug approaches to combat frailty, but human trials are needed and delivering such an anaerobic microbe in pill form remains a hurdle; the work was published in Gut and underscores the gut-muscle connection.

via Live Science|

#gut-microbiome #health #mediterranean-diet

science14 days ago•5 min saved

Aronia Juice's Metabolic Boost Depends on Your Gut Microbiome

A study using humanized mice found polyphenol-rich Aronia juice can shield against high-fat-diet–induced metabolic disruption, but benefits vary with the gut microbiome: mice with low-inflammatory microbiomes showed preserved gut diversity and favorable metabolic markers after Aronia treatment, while those with high-inflammatory microbiomes did not exhibit the same benefits.

via Indian Defence Review|

#aronia-juice #gut-microbiome #inflammation

science14 days ago•6 min saved

Gut Microbes Point to Simple B Vitamin Therapy for Parkinson's

A study links gut microbiome changes in Parkinson's disease to lower levels of riboflavin (B2) and biotin (B7), reduced short-chain fatty acids, and thinning of the intestinal mucus, suggesting that oral riboflavin and biotin supplementation could be a simple therapeutic approach; findings come from analyses of patients and controls across several countries, indicating a gut–brain pathway but the treatment would likely require personalized assessment.

via ScienceAlert|

#biotin #gut-microbiome #parkinsons-disease

health16 days ago•18 min saved

Black chokeberry juice linked to gut resilience and metabolic balance, study finds

A controlled mouse study using human gut microbiomes tested polyphenol-rich Aronia juice to see if it helps the host withstand a high-fat diet. Results showed Aronia juice modestly increased gut microbial diversity, boosted certain beneficial bacteria, and, in low-inflammation microbiomes, raised indoleacrylic acid—an antioxidant and gut-barrier supporter. Blood metabolites shifted in favorable directions (lower TMAO and higher phosphatidylcholines), suggesting improved barrier function and lipid handling. The work, conducted in mice, cannot be extrapolated to humans yet and does not claim a cure; further human studies are needed to assess any real-world health effects on blood sugar or blood pressure.

via Earth.com|

#aronia-melanocarpa #black-chokeberry #blood-sugar

health17 days ago•4 min saved

Fuel Your Gut, Protect Your Heart: 3 Science-Backed Habits

A Vanderbilt-led study linking gut bacteria–related metabolites to coronary heart disease identifies three practical habits to boost gut health and lower heart risk: eat mostly plant-based, high-fiber, minimally processed foods (prefer diverse fiber); cook from scratch to cut ultra-processed items; and exercise regularly, which supports a healthier gut microbiome and may reduce cardiovascular risk.

via Business Insider|

#gut-health #gut-microbiome #health

health17 days ago•6 min saved

Goldilocks Zone for Bowel Habits Tied to Overall Health, Study Finds

A 2024 ISB-led study of 1,425 generally healthy adults links how often people poop to overall health, identifying a 'Goldilocks' zone of once to twice daily; constipation or diarrhea were associated with microbiome shifts and blood markers of liver stress, suggesting that increasing fiber, water intake, and exercise could nudge people toward healthier bowel habits, though causality remains unproven.

via ScienceAlert|

#bowel-movement-frequency #constipation #diarrhea

health18 days ago•5 min saved

Living Together, Sharing Microbes: How Partners’ Bacteria May Shape Health

Cohabiting couples share a sizable portion of their microbiomes, with about 30% of gut bacteria and notable overlaps in oral and skin microbes, driven by shared environments and daily habits. Greater microbial diversity from living together can be linked to lower risks of IBS, cardiovascular disease and high blood sugar, but the health impact depends on which bacteria are shared; some bacteria can be beneficial, others harmful. Saliva exchange during kissing further spreads oral bacteria, and while overall effects are still being studied, the shared microbiome is a real and ongoing area of research.

via The Conversation|

#couples #gut-microbiome #health