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Bms

All articles tagged with #bms

Autoimmune CAR-T Trials Halt After Fatal IEC-HS Events
healthcare1 month ago

Autoimmune CAR-T Trials Halt After Fatal IEC-HS Events

Novartis has temporarily paused its autologous CD19 CAR-T program for autoimmune diseases after three IEC-HS–related deaths, affecting multiple phase 1/2 studies across lupus, systemic sclerosis, ANCA-associated vasculitis, myopathies and other conditions, with patient monitoring continuing. Bristol Myers Squibb has also paused enrollment in its autologous CD19 zola-cel autoimmune trials due to transient inflammatory events, though oncology programs remain active. Analysts suggest rapid manufacturing platforms (T-Charge, NEXT-T) may drive increased T‑cell expansion and toxicities, prompting a cautious safety review before resumption.

BMS, Nvidia push to build life sciences’ most powerful AI engine
technology2 months ago

BMS, Nvidia push to build life sciences’ most powerful AI engine

Bristol Myers Squibb is expanding its Nvidia-powered infrastructure with the DGX SuperPOD to create what it calls the most powerful, energy-efficient AI platform in life sciences, enabling hybrid human-AI science to accelerate R&D and improve decision quality across its pipeline; the move extends a multi-year collaboration with Nvidia and aligns with other pharma AI partnerships in the sector.

BMS inks $15B China-backed deal to fast-track Hengrui assets
business5 months ago

BMS inks $15B China-backed deal to fast-track Hengrui assets

Bristol Myers Squibb is striking a broad deal with Hengrui Pharma worth up to $15.2 billion, featuring $600 million upfront for 13 early-stage programs, ex-China rights to four oncology/hematology assets, and joint discovery on five candidates; Hengrui will gain access to BMS immunology assets in China, Hong Kong and Macau and lead early development to proof of concept, in a move that leverages China's reportedly faster timelines (50–70% quicker) to clinical proof of concept.