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Brain And Heart Regeneration

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New aging model hints at 156-year lifespans by tackling DNA damage
science1 month ago

New aging model hints at 156-year lifespans by tackling DNA damage

A July 2026 npj Aging paper proposes that removing the effects of somatic mutations could allow humans to live as long as 156 years, challenging the long-standing ~122-year limit. The model accounts for DNA damage but acknowledges other aging processes (mitochondrial dysfunction, epigenetic drift, telomere shortening, proteostasis loss). Experts say protecting DNA in non-regenerating organs like the brain and heart is crucial, while lifestyle measures—not smoking, healthy weight, good sleep, vaccines, and preventive care—can still meaningfully extend healthy years; there is no magic pill yet.