Miracle CRISPR treatment cures stage 4 colon cancer in a 12-patient trial
Emma Weston-Dimery, diagnosed with stage 4 colon cancer at 23, was one of 12 patients in a Phase 1 trial of CRISPR-Cas9 gene-edited immune cells. After cells were edited to better attack the cancer and reinfused in early 2023, two nodules disappeared within a month and the remaining cancer vanished by month two. She is now cancer-free, the only patient in the trial to achieve complete remission. The study showed mixed results for others, with some stabilization and several deaths due to the disease. A Phase 2 trial and a pill-form version of the therapy are planned, and Weston-Dimery is now an advocate for clinical trials and patient awareness.