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Bowel Cancer

All articles tagged with #bowel cancer

Pre-surgery pembrolizumab linked to zero recurrences in a small bowel cancer trial
health21 days ago

Pre-surgery pembrolizumab linked to zero recurrences in a small bowel cancer trial

In a 32-patient trial of stage 2–3 bowel cancer with MMR-deficient/MSI-high tumors, a short course of pembrolizumab before surgery kept all patients cancer-free for nearly three years; early data showed 59% had no signs of cancer at surgery, and long-term follow-up found no recurrences, a result that may surpass standard chemotherapy for this subset but is limited by size and specificity. Researchers also used tumor DNA blood tests to monitor response and aim to predict who will benefit. Presented at AACR 2026; longer follow-up is needed.

via Fox News|
#bowel-cancer#health#immunotherapy
Five subtle signs of bowel cancer you should not ignore
life-style24 days ago

Five subtle signs of bowel cancer you should not ignore

A health feature outlines five early warning signs of bowel cancer—blood in the stool, persistent changes in bowel habits, abdominal pain, bloating, and unexplained weight loss—and urges anyone experiencing these symptoms to see a GP promptly. The piece highlights the value of early reporting for better outcomes and explains NHS screening options, including at-home FIT tests and follow-up tests like colonoscopy or CT scans if results are positive.

via The Independent|
#blood#bowel-cancer#cancer
Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England
health24 days ago

Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England

England’s cancer data from 2001–2019 show rising cancer incidence among people under 50, with bowel and ovarian cancers increasing most notably. While obesity and certain behavioral factors contribute, they do not fully explain the trend, suggesting possible age-specific exposures or additional influences (reproductive history, early-life factors, diet, microbiome, and detection changes). The study is observational and cannot prove causation.

via SciTechDaily|
#bowel-cancer#cancer#england
Pre-Surgery Immunotherapy Sparks Near-Three-Year Cancer-Free Remission in Bowel Cancer
health27 days ago

Pre-Surgery Immunotherapy Sparks Near-Three-Year Cancer-Free Remission in Bowel Cancer

A UK-led NEOPRISM-CRC trial treated stage II/III MMR-deficient/MSI-H bowel cancer with up to nine weeks of pembrolizumab before surgery. After ~33 months of follow-up, none of the 32 patients have recurred, and 59% had no detectable cancer at surgery, suggesting preoperative immunotherapy may provide durable control compared with standard surgery followed by chemotherapy. Researchers are also using personalized blood tests and immune profiling to predict responders and monitor remaining disease.

via SciTechDaily|
#bowel-cancer#clinical-trial#health
Immunotherapy-First Bowel Cancer Trial Reports Zero Relapses After 33 Months
science1 month ago

Immunotherapy-First Bowel Cancer Trial Reports Zero Relapses After 33 Months

A UK-led NEOPRISM-CRC trial treated 32 patients with stage 2/3 bowel cancer using up to 9 weeks of pembrolizumab before surgery instead of post‑op chemotherapy. About 59% had no detectable cancer after treatment and surgery; after 33 months, none had a cancer relapse. The researchers highlight the potential for durable disease control with preoperative immunotherapy and are developing blood tests and immune profiling to predict responders, noting that roughly 25% relapse is expected with standard treatment after three years.

via Good News Network|
#bowel-cancer#cancer#clinical-trial
AI maps bowel cancer genetics to predict bevacizumab response
health1 month ago

AI maps bowel cancer genetics to predict bevacizumab response

Researchers from the Institute of Cancer Research and RCSI used PhenMap, an AI tool, to analyze tumour genetics in 117 European advanced bowel cancer patients treated with bevacizumab, identifying patterns that predict non-response and potentially sparing thousands from ineffective treatment and side effects; the team plans to broaden testing and validate the approach for broader clinical use.

via The Guardian|
#ai#bevacizumab#bowel-cancer
Rise of bowel cancer in under-50s prompts risk-factor clues and urgent habit changes
health2 months ago

Rise of bowel cancer in under-50s prompts risk-factor clues and urgent habit changes

Bowel cancer is rising among people under 50, prompting a Prospect study at King’s College London to identify common traits among younger patients; in the meantime, experts outline plausible risk factors you can act on now, including 50g/day of processed meat (about two bacon rashers) raising risk by ~18%, sugary drinks, ultra-processed foods, low daily fiber, alcohol consumed on an empty stomach, inflammatory bowel disease, and sedentary lifestyle. With an estimated 50–60% of cases potentially preventable, practical steps include boosting fiber intake, cutting processed/ultra-processed foods, reducing sugary drinks, avoiding alcohol on an empty stomach, and staying physically active.

via Daily Mail|
#bowel-cancer#diet#early-age
Rising early-onset bowel cancer: spot the signs and act
health3 months ago

Rising early-onset bowel cancer: spot the signs and act

Dr Mark Porter warns that bowel cancer is increasingly diagnosed in younger people, urging awareness of warning signs (persistent changes in bowel habits, rectal bleeding, anemia, weight loss) and prompt GP consultation, while stressing the importance of taking up bowel screening (FIT tests and colonoscopy) which can dramatically improve survival; UK invites typically 50–74 every two years, with continued testing options after 74 in some regions.

via The Times|
#bowel-cancer#early-onset-bowel-cancer#health
health3 months ago

35-year-old mum survives bowel cancer after long ulcerative colitis battle

A 35-year-old Texas mother with a long history of ulcerative colitis is diagnosed with an aggressive colorectal cancer after childbirth. She undergoes three surgeries to remove her large intestine and reconstruct a J-pouch, followed by a six-month chemotherapy course; she has remained cancer-free since 2013 and reports a markedly improved quality of life despite ongoing dietary adjustments.

via LADbible|
#bowel-cancer#chemotherapy#colorectal-cancer
health4 months ago

Bowel cancer screening threshold cut to boost early detection

NHS England will lower the home bowel cancer screening threshold for the FIT test from 120 to 80 micrograms of blood per gram of feces, making screening more sensitive and enabling earlier detection of cancers and high‑risk polyps. The change is expected to identify about 600 additional cancers and 2,000 more high‑risk polyps each year, with digital NHS App alerts and a nationwide rollout by March 2028, potentially reducing late‑stage diagnoses and saving around £32m a year.

via The Telegraph|
#bowel-cancer#early-detection#fit-test
health4 months ago

Pork fat ranks among the healthiest foods in BBC Good Food study

A BBC Good Food study ranks pork fat (lard) eighth on a list of the healthiest foods, suggesting it can be healthier than everyday vegetables like peas, lettuce and tomatoes due to its fats and nutrients; Cancer Research UK cautions that red and processed meats raise bowel cancer risk, while proponents point to organic, pasture-raised lard containing CLA and other fats, highlighting the importance of sourcing.

via LADbible|
#bbc-good-food#bowel-cancer#health