Tag

Bowel Cancer

All articles tagged with #bowel cancer

Five Hidden Cancer Signals People Mistake for Ageing or Stress
health8 days ago

Five Hidden Cancer Signals People Mistake for Ageing or Stress

GP Dr Anisha Patel explains that many people dismiss cancer symptoms as stress or ageing, delaying help and risking worse outcomes. The piece highlights five warning signs—unusual fatigue, changes in bowel habits, unexplained weight loss, persistent back pain, and persistent bloating—that should prompt a GP visit if they last or worsen. Delays in diagnosis can increase mortality, while early detection improves survival, so don’t dismiss new or unusual symptoms as simply getting older.

Young mum's bowel cancer alarm: don't ignore early signs
health-and-wellbeing2 months ago

Young mum's bowel cancer alarm: don't ignore early signs

A 45-year-old Melbourne mum of two ignored fatigue, low iron and blood in the stool until a colonoscopy revealed stage-3 bowel cancer, prompting surgery (with a temporary stoma) and six months of chemotherapy. Now in remission and under regular monitoring, she’s speaking out to urge Australians not to dismiss bowel changes as just pregnancy or aging, highlighting rising rates among younger people and backing the Poo Check awareness campaign to normalise conversations about bowel health.

Hidden Signs of Bowel Cancer You Might Miss
health2 months ago

Hidden Signs of Bowel Cancer You Might Miss

Medical experts warn that colorectal cancer can mimic IBS and remain undiagnosed. Common signs include unexplained weight loss, dark stools or rectal bleeding, new or worsening changes in bowel habits, and sudden overnight GI symptoms. They emphasize timely medical evaluation—especially for those over 45 or with persistent changes—since early detection via colonoscopy can improve outcomes.

Immunotherapy Before Surgery Sparks Three-Year Remission in Bowel Cancer Trial
health2 months ago

Immunotherapy Before Surgery Sparks Three-Year Remission in Bowel Cancer Trial

In the NEOPRISM-CRC trial, 32 patients with stage II/III MMR-deficient/MSI-high bowel cancer received three doses of pembrolizumab before planned surgery. Seventy percent? No—the article states 59% had no signs of disease after pembrolizumab ahead of surgery, and after nearly three years none of the 32 patients have experienced a recurrence, meaning all remained cancer-free. The results suggest neoadjuvant immunotherapy could change treatment for some bowel cancers and possibly reduce chemotherapy needs, though not all patients benefit. Researchers are exploring blood tests and immune profiling to predict responders, while NHS access to such therapy remains under consideration.

Pre-surgery pembrolizumab linked to zero recurrences in a small bowel cancer trial
health3 months ago

Pre-surgery pembrolizumab linked to zero recurrences in a small bowel cancer trial

In a 32-patient trial of stage 2–3 bowel cancer with MMR-deficient/MSI-high tumors, a short course of pembrolizumab before surgery kept all patients cancer-free for nearly three years; early data showed 59% had no signs of cancer at surgery, and long-term follow-up found no recurrences, a result that may surpass standard chemotherapy for this subset but is limited by size and specificity. Researchers also used tumor DNA blood tests to monitor response and aim to predict who will benefit. Presented at AACR 2026; longer follow-up is needed.

Five subtle signs of bowel cancer you should not ignore
life-style3 months ago

Five subtle signs of bowel cancer you should not ignore

A health feature outlines five early warning signs of bowel cancer—blood in the stool, persistent changes in bowel habits, abdominal pain, bloating, and unexplained weight loss—and urges anyone experiencing these symptoms to see a GP promptly. The piece highlights the value of early reporting for better outcomes and explains NHS screening options, including at-home FIT tests and follow-up tests like colonoscopy or CT scans if results are positive.

Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England
health3 months ago

Under-50 Cancer Surge: Bowel and Ovarian Rates Climb in England

England’s cancer data from 2001–2019 show rising cancer incidence among people under 50, with bowel and ovarian cancers increasing most notably. While obesity and certain behavioral factors contribute, they do not fully explain the trend, suggesting possible age-specific exposures or additional influences (reproductive history, early-life factors, diet, microbiome, and detection changes). The study is observational and cannot prove causation.

Pre-Surgery Immunotherapy Sparks Near-Three-Year Cancer-Free Remission in Bowel Cancer
health3 months ago

Pre-Surgery Immunotherapy Sparks Near-Three-Year Cancer-Free Remission in Bowel Cancer

A UK-led NEOPRISM-CRC trial treated stage II/III MMR-deficient/MSI-H bowel cancer with up to nine weeks of pembrolizumab before surgery. After ~33 months of follow-up, none of the 32 patients have recurred, and 59% had no detectable cancer at surgery, suggesting preoperative immunotherapy may provide durable control compared with standard surgery followed by chemotherapy. Researchers are also using personalized blood tests and immune profiling to predict responders and monitor remaining disease.

Immunotherapy-First Bowel Cancer Trial Reports Zero Relapses After 33 Months
science4 months ago

Immunotherapy-First Bowel Cancer Trial Reports Zero Relapses After 33 Months

A UK-led NEOPRISM-CRC trial treated 32 patients with stage 2/3 bowel cancer using up to 9 weeks of pembrolizumab before surgery instead of post‑op chemotherapy. About 59% had no detectable cancer after treatment and surgery; after 33 months, none had a cancer relapse. The researchers highlight the potential for durable disease control with preoperative immunotherapy and are developing blood tests and immune profiling to predict responders, noting that roughly 25% relapse is expected with standard treatment after three years.

AI maps bowel cancer genetics to predict bevacizumab response
health4 months ago

AI maps bowel cancer genetics to predict bevacizumab response

Researchers from the Institute of Cancer Research and RCSI used PhenMap, an AI tool, to analyze tumour genetics in 117 European advanced bowel cancer patients treated with bevacizumab, identifying patterns that predict non-response and potentially sparing thousands from ineffective treatment and side effects; the team plans to broaden testing and validate the approach for broader clinical use.

Rise of bowel cancer in under-50s prompts risk-factor clues and urgent habit changes
health5 months ago

Rise of bowel cancer in under-50s prompts risk-factor clues and urgent habit changes

Bowel cancer is rising among people under 50, prompting a Prospect study at King’s College London to identify common traits among younger patients; in the meantime, experts outline plausible risk factors you can act on now, including 50g/day of processed meat (about two bacon rashers) raising risk by ~18%, sugary drinks, ultra-processed foods, low daily fiber, alcohol consumed on an empty stomach, inflammatory bowel disease, and sedentary lifestyle. With an estimated 50–60% of cases potentially preventable, practical steps include boosting fiber intake, cutting processed/ultra-processed foods, reducing sugary drinks, avoiding alcohol on an empty stomach, and staying physically active.

Rising early-onset bowel cancer: spot the signs and act
health6 months ago

Rising early-onset bowel cancer: spot the signs and act

Dr Mark Porter warns that bowel cancer is increasingly diagnosed in younger people, urging awareness of warning signs (persistent changes in bowel habits, rectal bleeding, anemia, weight loss) and prompt GP consultation, while stressing the importance of taking up bowel screening (FIT tests and colonoscopy) which can dramatically improve survival; UK invites typically 50–74 every two years, with continued testing options after 74 in some regions.

health6 months ago

35-year-old mum survives bowel cancer after long ulcerative colitis battle

A 35-year-old Texas mother with a long history of ulcerative colitis is diagnosed with an aggressive colorectal cancer after childbirth. She undergoes three surgeries to remove her large intestine and reconstruct a J-pouch, followed by a six-month chemotherapy course; she has remained cancer-free since 2013 and reports a markedly improved quality of life despite ongoing dietary adjustments.