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Case Report

All articles tagged with #case report

Testosterone Therapy Triggers Psychosis in a Man with Klinefelter Syndrome
health7 days ago

Testosterone Therapy Triggers Psychosis in a Man with Klinefelter Syndrome

A 45-year-old man on testosterone for osteoporosis developed paranoia and hearing voices about a year into therapy; stopping testosterone led to rapid resolution of symptoms, and he was later restarted on testosterone with close monitoring. He was found to have Klinefelter syndrome, which may increase psychiatric risk, underscoring the need for baseline mental-health screening and vigilant monitoring when initiating testosterone, especially in vulnerable patients.

via Gizmodo|
#case-report#health#klinefelter-syndrome
Testosterone Therapy Linked to Acute Psychosis in Man With Klinefelter Syndrome
mental-health8 days ago

Testosterone Therapy Linked to Acute Psychosis in Man With Klinefelter Syndrome

A case report describes a 45-year-old man who developed severe psychosis—hallucinations and hearing voices from his body—after a year of injectable testosterone for infertility and osteoporosis. He was later diagnosed with Klinefelter syndrome (XXY). Stopping testosterone and treating with antipsychotics led to recovery, and a cautious reintroduction at a lower dose with close monitoring did not prompt a relapse. The authors emphasize that this is a single case and does not prove causation, but hormone fluctuations may trigger psychiatric crises in vulnerable individuals, underscoring the need for psychiatric screening during hormone therapies.

via PsyPost|
#case-report#hormone-replacement-therapy#klinefelter-syndrome
Wedding Joy Sparks Rare Heart Syndrome in a Mother
health1 month ago

Wedding Joy Sparks Rare Heart Syndrome in a Mother

A 65-year-old mother developed the rare happy heart syndrome, a form of takotsubo cardiomyopathy, after extreme happiness at her daughter's wedding. She presented with chest pain and shortness of breath, was treated in intensive care for suspected acute coronary syndrome, but arteries were normal and imaging showed the characteristic left-ventricular ballooning. After hospitalization she fully recovered, underscoring that intense joy can, in rare cases, trigger serious heart problems and must be recognized by clinicians.

via Gizmodo|
#cardiology#case-report#happy-heart-syndrome
Itchy rash uncovers rare syphilis with neurosyphilis in an elderly man
health1 month ago

Itchy rash uncovers rare syphilis with neurosyphilis in an elderly man

An 83-year-old man in Belgium presented with facial nerve palsy, fever, anemia, and liver/kidney abnormalities. A severely itchy rash prompted testing that revealed Treponema pallidum infection, leading to a diagnosis of secondary syphilis with early neurosyphilis. He was treated with a 14‑day IV penicillin course, after an initial injection, with improvement and normalization of labs. The case highlights atypical, multisystem presentation of syphilis (including potential latent reactivation) and CNS involvement; public health authorities and his wife were notified/tested.

via Live Science|
#case-report#health#neurosyphilis
Hearing Loss Behind the Voices: A Case Reframes Auditory Hallucinations
health1 month ago

Hearing Loss Behind the Voices: A Case Reframes Auditory Hallucinations

A Canadian woman in her 50s experienced voices for years and was treated for unspecified psychosis with multiple antipsychotics, but later tests revealed bilateral sensorineural hearing loss. Even after fitting with hearing aids, the voices persisted, while brain scans and blood tests were normal and her daily functioning remained intact—suggesting the hallucinations arose from sensory deprivation rather than a psychotic disorder. The case underscores that hearing voices does not always indicate psychosis and recommends early hearing assessments and coping-focused psychotherapy to manage persistent hallucinations when hearing loss is present.

via Live Science|
#auditory-hallucinations#case-report#health
Rare European Eye Worm Detected in U.S. Eyelid Case, First of Its Kind
health1 month ago

Rare European Eye Worm Detected in U.S. Eyelid Case, First of Its Kind

A 74-year-old California man developed a firm eyelid nodule after an insect bite; an MRI suggested a chalazion, but surgical removal and genetic testing identified the culprit as a nematode, Dirofilaria repens, a parasite common in Europe/Asia and reportedly the first such human case documented in the United States. The worm likely arrived via local animal hosts and mosquito vectors; humans are incidental hosts. The patient recovered after removal, and researchers urge continued surveillance of D. repens in North America amid expanding mosquito populations.

via Gizmodo|
#case-report#dirofilaria-repens#eyelid
Ontario boy dies of rabies after bat contact, prompting warning on urgent post-exposure care
health1 month ago

Ontario boy dies of rabies after bat contact, prompting warning on urgent post-exposure care

An 11-year-old in northern Ontario woke to a bat on his face and, despite no visible bite, later died from rabies—the first locally acquired human case in Ontario since 1967. The case highlights the importance of seeking immediate medical evaluation after any direct bat contact, since rabies is almost always fatal once symptoms appear, though prompt post‑exposure treatment can prevent infection.

via USA Today|
#bat-exposure#case-report#health
High-dose psilocybin briefly revives function in advanced Alzheimer's: a case study
science2 months ago

High-dose psilocybin briefly revives function in advanced Alzheimer's: a case study

A published Frontiers in Neuroscience case report describes an 80-year-old woman with advanced Alzheimer's who temporarily regained urinary continence, walking ability, self-care, and conversational capacity after a single five-gram dose of psilocybin-containing mushrooms (with a follow-up three-gram session showing continued improved verbal expression). While the improvements spanned multiple domains and persisted for weeks, researchers caution that this is a single observational case without controls or standardized testing, and not evidence of a cure. The findings suggest dormant brain-network capacities may be temporarily re-engaged by psychedelic-induced neuroplasticity, highlighting the need for formal, controlled trials and safety assessments, particularly in vulnerable older adults; ongoing studies like UC Berkeley's PLASTICITY aim to explore aging brains and neuroplasticity with psychedelics.

via PsyPost|
#alzheimers-disease#case-report#neuroplasticity
Dormant Congenital Dermal Sinus Reawakened by Leishmaniasis in Buttock
health2 months ago

Dormant Congenital Dermal Sinus Reawakened by Leishmaniasis in Buttock

A middle‑aged woman develops a draining buttock lesion due to cutaneous leishmaniasis, revealing a decades‑old congenital dermal sinus that was reactivated by the parasite; after medical treatment and surgical removal, doctors confirmed no spinal connection, and the case is highlighted to raise awareness of this rare presentation of leishmaniasis, a neglected tropical disease affecting over a million people annually.

via ScienceAlert|
#case-report#congenital-anomaly#cutaneous-infection
Tiny Brain, Huge Ventricles: A Surprising Case Behind Leg Weakness
health2 months ago

Tiny Brain, Huge Ventricles: A Surprising Case Behind Leg Weakness

A 44-year-old man in France presented with two weeks of left‑leg weakness. Neuroimaging showed an abnormally small brain (about half the average size) with massive fluid buildup and extremely dilated ventricles pushing brain tissue against the skull, a state likely causing his weakness. He had a history of an infancy shunt that was removed at 14. Doctors drained the excess fluid and inserted a new intracranial shunt, with his neurological exams improving over weeks. Neuropsych tests placed his IQ at about 75 and remained unchanged. The Lancet case report uses this vignette to reflect on human brain growth and its drivers, illustrating how a very small brain can be linked to significant clinical changes when ventricles are enlarged.

via Live Science|
#brain#case-report#health
Psychedelic mushrooms briefly revive speech in late-stage Alzheimer's case
science2 months ago

Psychedelic mushrooms briefly revive speech in late-stage Alzheimer's case

A case report in Frontiers in Neuroscience describes an elderly woman with advanced Alzheimer’s disease who, after two sessions of psilocybin-containing mushrooms, spontaneously regained autobiographical speech, showed improved memory recall, continence, and mobility, and engaged more emotionally. The benefits lasted at least a month, but the study involved a single patient with no control group, so researchers caution that larger, controlled trials are needed to confirm any potential therapeutic effect and safety.

via Yahoo|
#alzheimers-disease#brain-function#case-report
Stress-Linked Hematohidrosis: Rare Bleeding Case in an Indian Boy
health2 months ago

Stress-Linked Hematohidrosis: Rare Bleeding Case in an Indian Boy

An 11-year-old Indian boy experienced episodes of bleeding from the eyes, nose, and ears during periods of academic stress. After comprehensive testing showed no bleeding disorder, psychiatrists attributed the symptoms to stress-related hematohidrosis, a very rare condition with fewer than 50 reported cases. The patient was treated with propranolol and cognitive behavioral therapy to manage stress; within months his episodes diminished and he became symptom-free, underscoring a potential link between psychological stress and this unusual bleeding phenomenon (though causation remains unproven).

via Live Science|
#case-report#health#hematohidrosis
Whip-marked rash after shiitake mushrooms reveals a rare dermatitis case
health3 months ago

Whip-marked rash after shiitake mushrooms reveals a rare dermatitis case

A 23-year-old Florida woman developed whip‑mark–like red streaks on her back two days after eating shiitake mushrooms. Doctors diagnosed shiitake dermatitis, a rare inflammatory skin reaction linked to lentinan in the mushroom, with risk possibly influenced by how the mushrooms are grown. She received a topical steroid, an antifungal, and antihistamines/corticosteroids; the rash resolved in about three weeks, and she continued consuming shiitake mushrooms without recurrence.

via Live Science|
#case-report#dermatology#health