Tag

Denosumab

All articles tagged with #denosumab

health20 days ago•2 min saved

Denosumab May Shield Joints in Osteoporosis Patients

Using Japanese claims data (2015–2024), new denosumab users had a 16% lower 3-year risk of developing osteoarthritis vs new oral bisphosphonate users (relative risk 0.84; 95% CI 0.73–0.89), especially for knee and hip OA. The benefit was not significant for those who switched from bisphosphonates to denosumab. Given the observational design and potential confounding, findings should be interpreted with caution and require clinically validated OA outcomes.

via Medscape|

#bisphosphonates #denosumab #health

health3 years ago•3 min saved

NIH Clinical Trial Shows Promise for Rare Bone Disorder Treatment

A clinical trial conducted by the National Institutes of Health (NIH) has found that denosumab, a medication used to treat bone problems from osteoporosis and cancer, significantly reduced abnormal bone turnover in adults with fibrous dysplasia, a rare disease marked by weak and misshapen bones. The study of eight participants showed that denosumab may improve patients’ quality of life by enabling healthy bone formation. However, abnormal bone turnover returned for all but one of the patients after they stopped taking the medication, indicating that clinicians must factor in these risks when treating patients.

via National Institutes of Health (.gov)|

#bone-turnover #clinical-trial #denosumab