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Engineered Bacteria

All articles tagged with #engineered bacteria

science25 days ago•14 min saved

Smart Probiotic GIFT: Sensing Sugar, Releasing GLP-1

Researchers from East China Normal University engineered an oral probiotic called GIFT that resides briefly in the gut, senses real-time blood glucose elevations, and autonomously secretes GLP-1 to lower glucose levels. In tests with mice and non-human primates, it improved glycemic control and lipid profiles, and human trials are planned, offering a potential on-demand alternative to some insulin regimens and traditional GLP-1 therapies in the future.

via Daily Kos|

#diabetes #diabetes-care #engineered-bacteria

science6 months ago•42 min saved

Bacteria Turn Trash Plastic into Parkinson’s Medication

Researchers at the University of Edinburgh engineered E. coli to break down post-consumer PET plastic into L-DOPA, the frontline drug for Parkinson’s disease, marking the first demonstration of a biology-based route from plastic waste to a pharmaceutical and signaling a potentially greener, scalable way to produce medicines. The work, part of the Carbon-Loop Sustainable Biomanufacturing Hub with £14 million in EPSRC funding, aims to optimize industrial-scale production and reduce reliance on fossil-fuel–based pharmaceutical processes.

via Good News Network|

#engineered-bacteria #l-dopa #parkinsons-disease

medical-research2 years ago•8 min saved

"Engineered Skin Microbes Deliver Acne Treatment Molecules in Mice"

Researchers have developed an engineered skin microbe that delivers a sebum modulator to mice, potentially offering a new approach to treating skin conditions. This study adds to the growing body of research on engineered bacteria for medical applications, including skin health and cancer immunotherapy. The skin microbiome and its interaction with skin conditions like acne are areas of active research, with potential implications for developing new treatments.

via Nature.com|

#engineered-bacteria #medical-research #sebum-modulator