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Find Ckd

All articles tagged with #find ckd

health16 days ago•11 min saved

Finerenone extends kidney protection to non-diabetic CKD, early FIND-CKD data show

Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, continues to show kidney and cardiovascular benefits in chronic kidney disease, with FIND-CKD data indicating protection even in patients without diabetes; however, there is a modest rise in serum potassium (about 0.12 mmol/L) and hyperkalemia events occurred in 17% of treated patients versus 13.3% in placebo, overall suggesting good safety and tolerability.

via Nature|

#chronic-kidney-disease #find-ckd #finerenone

health1 month ago•7 min saved

Finerenone Extends Kidney Disease Benefits to Non-Diabetic Patients

A NEJM-identified FIND-CKD trial shows finerenone, previously used for diabetic CKD, also slows kidney function decline in adults with CKD who do not have diabetes. In 1,584 non-diabetic participants, finerenone added to standard therapy (ACE inhibitors/ARBs) significantly slowed eGFR loss over about 2.5 years and reduced the risk of major kidney events, heart failure hospitalization, and cardiovascular death by roughly 23%, while also lowering urinary protein by over 40%. The drug was well tolerated, suggesting it could broaden treatment to the roughly 800 million non-diabetic CKD patients worldwide.

via SciTechDaily|

#chronic-kidney-disease #find-ckd #finerenone