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Chronic Kidney Disease

All articles tagged with #chronic kidney disease

CKM Syndrome: A five-stage cascade linking obesity, diabetes, kidney disease, and heart disease
health15 days ago

CKM Syndrome: A five-stage cascade linking obesity, diabetes, kidney disease, and heart disease

CKM syndrome ties obesity, metabolic disorders, kidney disease, and cardiovascular disease into a five-stage continuum from optimal health (Stage 0) to established cardiovascular disease (Stage 4); early detection through broad risk screening and management with lifestyle changes (weight loss, DASH/Mediterranean diet, exercise, sleep, stress reduction) and medications (SGLT2 inhibitors, GLP-1 agonists) can slow progression and protect heart and kidney function.

Bethenny Frankel reveals she was misdiagnosed with a major health issue
celebrities20 days ago

Bethenny Frankel reveals she was misdiagnosed with a major health issue

Bethenny Frankel said in an Instagram video that a network of medical specialists concluded she had been misdiagnosed with a “pretty major” condition, months after she disclosed a stage 2 chronic kidney disease. While doctors can’t pinpoint a specific cause, she cites possible links to a past traumatic allergy incident, hydration issues, and low blood pressure, and urges others to stay thorough with blood work and their medical care.

Bethenny Frankel: major health misdiagnosis prompts cautious health update
entertainment21 days ago

Bethenny Frankel: major health misdiagnosis prompts cautious health update

Bethenny Frankel says she was misdiagnosed with a major health condition after joining a “very legitimate” medical network that cross-checks lab results and supplements; doctors reportedly are convinced of the misdiagnosis, but she did not specify the condition and urged fans to be thorough with medical care and not rely on ChatGPT for health advice. She has previously disclosed a January diagnosis of chronic kidney disease, noting her condition can be managed with lifestyle changes.

Bethenny Frankel Says Doctors Think She Was Misdiagnosed With a Major Health Issue
entertainment21 days ago

Bethenny Frankel Says Doctors Think She Was Misdiagnosed With a Major Health Issue

Bethenny Frankel revealed that a medical community reviewing her health markers believes she has been misdiagnosed with a major illness, urging followers to get thorough labs and seek multiple opinions. She has previously shared that she’s dealing with Stage 2 chronic kidney disease and emphasized being proactive about one’s health.

CKD in Diabetes: Diet, Meds, and Safer Bladder Treatments
health1 month ago

CKD in Diabetes: Diet, Meds, and Safer Bladder Treatments

Dr. Roach says CKD management hinges on solid diabetes care and lifestyle, not supplements: keep sodium under 2,000 mg daily, favor plant-based protein, and tightly control blood pressure with ACE inhibitors/ARBs (target ~130 mm Hg, possibly lower). Medications like finerenone may help when BP goals aren’t reached; SGLT2 inhibitors (e.g., empagliflozin) slow kidney decline, and GLP-1 drugs can offer heart/kidney protection with weight loss. An A1C goal of about 6.5–7.5% is typical but individualized. For bladder symptoms, long-term anticholinergics such as oxybutynin carry a small dementia risk; trospium has lower risk, and beta-3 agonists (mirabegron, vibegron) are often preferred when possible.

Sunisa Lee Signals Comeback Ahead of LA 2028
sports1 month ago

Sunisa Lee Signals Comeback Ahead of LA 2028

Sunisa Lee, the six-time Olympic medallist who won Tokyo 2020 all-around gold, team silver and uneven bars bronze and helped the U.S. to team gold in Paris 2024, announced her return to gymnastics after a two-year hiatus, sharing an Instagram video in which she says 'I'm back' and hints at chasing LA 2028. She cites readiness after a health battle—diagnosed chronic kidney disease in 2023—and mental-health struggles—while noting she feels good with less daily training. Jade Carey also recently returned from a similar break, and Simone Biles remains unsure about competing in LA.

Oxalate drives systemic inflammation and heart injury in kidney disease
health1 month ago

Oxalate drives systemic inflammation and heart injury in kidney disease

A study in Cardiovascular Research found that oxalate accumulation in CKD activates systemic IL-17A–driven inflammation, causing kidney damage and heart dysfunction in mice; blocking IL-17A improved kidney function and reduced inflammation and fibrosis, highlighting an oxalate–IL-17A axis as a potential therapeutic target and a way to identify high-risk CKD patients.

Finerenone extends kidney protection to non-diabetic CKD, early FIND-CKD data show
health2 months ago

Finerenone extends kidney protection to non-diabetic CKD, early FIND-CKD data show

Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, continues to show kidney and cardiovascular benefits in chronic kidney disease, with FIND-CKD data indicating protection even in patients without diabetes; however, there is a modest rise in serum potassium (about 0.12 mmol/L) and hyperkalemia events occurred in 17% of treated patients versus 13.3% in placebo, overall suggesting good safety and tolerability.

Finerenone Extends Kidney Disease Benefits to Non-Diabetic Patients
health2 months ago

Finerenone Extends Kidney Disease Benefits to Non-Diabetic Patients

A NEJM-identified FIND-CKD trial shows finerenone, previously used for diabetic CKD, also slows kidney function decline in adults with CKD who do not have diabetes. In 1,584 non-diabetic participants, finerenone added to standard therapy (ACE inhibitors/ARBs) significantly slowed eGFR loss over about 2.5 years and reduced the risk of major kidney events, heart failure hospitalization, and cardiovascular death by roughly 23%, while also lowering urinary protein by over 40%. The drug was well tolerated, suggesting it could broaden treatment to the roughly 800 million non-diabetic CKD patients worldwide.

Global Kidney Disease Surges to 800 Million, Redefining Public Health Priority
health-and-medicine2 months ago

Global Kidney Disease Surges to 800 Million, Redefining Public Health Priority

A Global Burden of Disease 2023 analysis published in The Lancet finds chronic kidney disease affects about 14% of adults worldwide—roughly 788 million people in 2023—pushing CKD into the top 10 causes of death and making it a major driver of cardiovascular disease. Most cases are early, so early detection and access to treatments (dialysis, transplantation, and newer kidney‑protective therapies) are crucial, yet access remains uneven in low‑income regions. The study calls for expanded screening and better treatment access to slow progression and reduce heart‑related risk as CKD policies gain global prominence.

Aldosterone-Blocking Pill Shows Dual Benefit for CKD Patients with Hypertension
health3 months ago

Aldosterone-Blocking Pill Shows Dual Benefit for CKD Patients with Hypertension

An experimental aldosterone synthase inhibitor, baxdrostat, lowered systolic BP by 8.1 mm Hg more than placebo and cut urine albumin by 55% after 26 weeks in 192 CKD patients with uncontrolled hypertension on standard therapy, hinting at kidney and cardiovascular protection; however, hyperkalemia was more common (41% vs 5%), and serious adverse events were higher (9% vs 3%). Baxdrostat is not FDA-approved, and Phase 3 trials (including BaxHTN and Bax24) are under way, with exploring combinations like baxdrostat plus dapagliflozin.

JC virus can trigger deadly brain disease in chronic kidney disease patients, case study reveals
health5 months ago

JC virus can trigger deadly brain disease in chronic kidney disease patients, case study reveals

A case study reports progressive multifocal leukoencephalopathy (PML) caused by JC virus activation in a 72-year-old patient with stage-5 CKD, suggesting CKD can create noncanonical immunosuppression that predisposes to JC virus–related brain damage. The JC virus is common and usually latent but can reactivate to destroy brain myelin, diagnosed by MRI lesions and JC virus DNA in CSF; the patient died two days after diagnosis, highlighting the seriousness of PML in CKD as CKD prevalence rises.

Covid infection tied to a sharp rise in kidney disease risk, study finds
health5 months ago

Covid infection tied to a sharp rise in kidney disease risk, study finds

A Penn State College of Medicine study of about 3 million Americans finds Covid-19 infection is linked to a 54% higher risk of developing kidney disease in the following year, prompting calls for regular kidney monitoring after infection—especially for people with diabetes or high blood pressure. Chronic kidney disease affects roughly 7.2 million people in the UK with about 45,000 deaths per year, and numbers could rise further, possibly due to lasting kidney damage from Covid.

Bethenny Frankel Reveals Stage 3A CKD, Urges Fans to Get Tested
entertainment6 months ago

Bethenny Frankel Reveals Stage 3A CKD, Urges Fans to Get Tested

Reality star Bethenny Frankel told followers on Instagram that she has stage 3A chronic kidney disease and a liver nodule, urging fans to get tested. She emphasized hydration, cautioned that supplements should be discussed with a doctor due to potential interactions, and said she’ll make dietary changes (like avoiding ice cream and ibuprofen) while monitoring her condition with her physician.

Fruits to Avoid and Healthy Alternatives for Kidney Health
health8 months ago

Fruits to Avoid and Healthy Alternatives for Kidney Health

Certain fruits like bananas, oranges, avocados, and dried fruits can be harmful to individuals with chronic kidney disease due to their high potassium and sugar content, while fruits like watermelon, berries, and pineapple are beneficial for kidney health. It's important for those with kidney issues to choose their fruit intake carefully and consult with healthcare professionals.