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Chronic Kidney Disease

All articles tagged with #chronic kidney disease

Finerenone extends kidney protection to non-diabetic CKD, early FIND-CKD data show
health16 days ago

Finerenone extends kidney protection to non-diabetic CKD, early FIND-CKD data show

Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, continues to show kidney and cardiovascular benefits in chronic kidney disease, with FIND-CKD data indicating protection even in patients without diabetes; however, there is a modest rise in serum potassium (about 0.12 mmol/L) and hyperkalemia events occurred in 17% of treated patients versus 13.3% in placebo, overall suggesting good safety and tolerability.

via Nature|
#chronic-kidney-disease#find-ckd#finerenone
Finerenone Extends Kidney Disease Benefits to Non-Diabetic Patients
health1 month ago

Finerenone Extends Kidney Disease Benefits to Non-Diabetic Patients

A NEJM-identified FIND-CKD trial shows finerenone, previously used for diabetic CKD, also slows kidney function decline in adults with CKD who do not have diabetes. In 1,584 non-diabetic participants, finerenone added to standard therapy (ACE inhibitors/ARBs) significantly slowed eGFR loss over about 2.5 years and reduced the risk of major kidney events, heart failure hospitalization, and cardiovascular death by roughly 23%, while also lowering urinary protein by over 40%. The drug was well tolerated, suggesting it could broaden treatment to the roughly 800 million non-diabetic CKD patients worldwide.

via SciTechDaily|
#chronic-kidney-disease#find-ckd#finerenone
Global Kidney Disease Surges to 800 Million, Redefining Public Health Priority
health-and-medicine1 month ago

Global Kidney Disease Surges to 800 Million, Redefining Public Health Priority

A Global Burden of Disease 2023 analysis published in The Lancet finds chronic kidney disease affects about 14% of adults worldwide—roughly 788 million people in 2023—pushing CKD into the top 10 causes of death and making it a major driver of cardiovascular disease. Most cases are early, so early detection and access to treatments (dialysis, transplantation, and newer kidney‑protective therapies) are crucial, yet access remains uneven in low‑income regions. The study calls for expanded screening and better treatment access to slow progression and reduce heart‑related risk as CKD policies gain global prominence.

via ScienceDaily|
#cardiovascular-disease#chronic-kidney-disease#global-burden-of-disease
Aldosterone-Blocking Pill Shows Dual Benefit for CKD Patients with Hypertension
health2 months ago

Aldosterone-Blocking Pill Shows Dual Benefit for CKD Patients with Hypertension

An experimental aldosterone synthase inhibitor, baxdrostat, lowered systolic BP by 8.1 mm Hg more than placebo and cut urine albumin by 55% after 26 weeks in 192 CKD patients with uncontrolled hypertension on standard therapy, hinting at kidney and cardiovascular protection; however, hyperkalemia was more common (41% vs 5%), and serious adverse events were higher (9% vs 3%). Baxdrostat is not FDA-approved, and Phase 3 trials (including BaxHTN and Bax24) are under way, with exploring combinations like baxdrostat plus dapagliflozin.

via SciTechDaily|
#aldosterone#baxdrostat#chronic-kidney-disease
JC virus can trigger deadly brain disease in chronic kidney disease patients, case study reveals
health3 months ago

JC virus can trigger deadly brain disease in chronic kidney disease patients, case study reveals

A case study reports progressive multifocal leukoencephalopathy (PML) caused by JC virus activation in a 72-year-old patient with stage-5 CKD, suggesting CKD can create noncanonical immunosuppression that predisposes to JC virus–related brain damage. The JC virus is common and usually latent but can reactivate to destroy brain myelin, diagnosed by MRI lesions and JC virus DNA in CSF; the patient died two days after diagnosis, highlighting the seriousness of PML in CKD as CKD prevalence rises.

via Ars Technica|
#chronic-kidney-disease#health#immunosuppression
Covid infection tied to a sharp rise in kidney disease risk, study finds
health4 months ago

Covid infection tied to a sharp rise in kidney disease risk, study finds

A Penn State College of Medicine study of about 3 million Americans finds Covid-19 infection is linked to a 54% higher risk of developing kidney disease in the following year, prompting calls for regular kidney monitoring after infection—especially for people with diabetes or high blood pressure. Chronic kidney disease affects roughly 7.2 million people in the UK with about 45,000 deaths per year, and numbers could rise further, possibly due to lasting kidney damage from Covid.

via dailymail.co.uk|
#chronic-kidney-disease#covid-19#health
Bethenny Frankel Reveals Stage 3A CKD, Urges Fans to Get Tested
entertainment4 months ago

Bethenny Frankel Reveals Stage 3A CKD, Urges Fans to Get Tested

Reality star Bethenny Frankel told followers on Instagram that she has stage 3A chronic kidney disease and a liver nodule, urging fans to get tested. She emphasized hydration, cautioned that supplements should be discussed with a doctor due to potential interactions, and said she’ll make dietary changes (like avoiding ice cream and ibuprofen) while monitoring her condition with her physician.

via The Daily Beast|
#bethenny-frankel#chronic-kidney-disease#entertainment
Fruits to Avoid and Healthy Alternatives for Kidney Health
health6 months ago

Fruits to Avoid and Healthy Alternatives for Kidney Health

Certain fruits like bananas, oranges, avocados, and dried fruits can be harmful to individuals with chronic kidney disease due to their high potassium and sugar content, while fruits like watermelon, berries, and pineapple are beneficial for kidney health. It's important for those with kidney issues to choose their fruit intake carefully and consult with healthcare professionals.

via Times of India|
#chronic-kidney-disease#fruits#health
Research Warns Against Extreme Temperatures for Kidney Disease Patients
health6 months ago

Research Warns Against Extreme Temperatures for Kidney Disease Patients

Research shows that climate change-induced extreme heat and cold contribute to the rise in chronic kidney disease (CKD) globally, with dehydration from temperature extremes damaging kidneys. CKD affects over 788 million people worldwide, with key risk factors including high salt diets, high blood pressure, obesity, and non-optimal temperatures. Greater prevention, screening, and accessible treatments are needed to address this growing health issue.

via Cebu Daily News|
#chronic-kidney-disease#climate-change#dehydration
Global Surge in Cases Elevates Killer Condition to Top 10 Causes of Death
health8 months ago

Global Surge in Cases Elevates Killer Condition to Top 10 Causes of Death

Chronic kidney disease has become the ninth leading cause of death worldwide, with cases nearly doubling from 1990 to 2023, driven by risk factors like high blood sugar, blood pressure, and BMI. Most cases are in early stages but often go undiagnosed, emphasizing the need for increased testing and access to treatment to prevent progression to dialysis or transplantation. The disease's rising prevalence highlights its importance as a major public health concern.

via AOL.com|
#chronic-kidney-disease#early-diagnosis#global-health
Global Rise in Kidney Disease: A Silent Killer Affecting 800 Million
health8 months ago

Global Rise in Kidney Disease: A Silent Killer Affecting 800 Million

Chronic kidney disease (CKD) affects nearly 800 million people worldwide and is among the top 10 causes of death, often remaining asymptomatic in early stages. Key risk factors include high blood pressure, high blood glucose, and high BMI. Early detection through regular testing and managing risk factors can slow progression and prevent severe complications.

via Times of India|
#chronic-kidney-disease#ckd#early-detection
Avoiding Common Protein Mistakes for Kidney Health and Weight Loss
health11 months ago

Avoiding Common Protein Mistakes for Kidney Health and Weight Loss

Excessive consumption of animal proteins, reliance on unregulated protein powders, neglecting routine kidney checks, ignoring plant-based proteins, and personal risk factors can harm kidney health. To protect kidneys, it's important to balance protein sources, monitor intake, and undergo regular screenings, especially for high-risk groups.

via The Times of India|
#chronic-kidney-disease#health#kidney-health