Wood frogs pull off a winter freeze—icing up most of their body water and rebooting in spring
Wood frogs can freeze about 65% of their body water as extracellular ice each winter, stopping heartbeat and breathing for months; they survive by keeping cells intact, then thaw and restart life in spring, aided by high blood glucose that acts as a natural cryoprotectant—researchers hope to apply this to organ banking and cryopreservation.
