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Herpesviridae

All articles tagged with #herpesviridae

health1 month ago•6 min saved

Dormant viruses awaken during COVID-19, potentially driving severity and long COVID

A study of 1,150 hospitalized COVID-19 patients found reactivation of dormant viruses from the Herpesviridae and Anelloviridae families in about 48% of cases, with HSV1 and CMV reactivating around day 20 and detection in nasal or blood samples linked to greater disease severity and higher 1-year mortality. Notably, Anelloviridae reactivation months after illness was associated with fatigue and disability (long COVID). The study shows association, not causation, and involved unvaccinated patients with early SARS-CoV-2 strains, so more research is needed to understand implications for prognosis and treatment."

via Medical News Today|

#anelloviridae #covid-19 #health

science2 months ago•89 min saved

Chronic Virus Reactivation Linked to Severity and Long COVID in COVID-19 Patients

A large, longitudinal study of 1,154 hospitalized COVID-19 patients using multi-omic analyses found significant reactivation of chronic viruses, especially Herpesviridae (EBV, CMV, HSV) and Anelloviridae, during acute illness with distinct timing for different viruses. Reactivation correlated with greater disease severity and adverse outcomes and persisted into convalescence, with Anelloviridae associated with long COVID. Although causality isn’t established, the results show frequent viral reactivation in immunocompetent patients during severe illness and reveal immune, transcriptomic, and metabolic changes linked to reactivation, offering potential prognostic and therapeutic insights for acute COVID-19 and long COVID.

via Nature|

#anelloviridae #herpesviridae #long-covid