Fiber and Prif Proteins Redirect Gut Bacteria Toward Healthier Metabolites
Two Princeton-led studies show that fiber and indigestible plant proteins (Prif) steer gut bacteria away from breaking down the intestinal mucus and toward producing healthier phenylalanine-derived metabolites, while reducing harmful tyrosine-derived ones; plus host cells also produce many indoles and phenols—together shaping the body's metabolite profile and guiding nuanced nutrition and therapies.