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Jama Network Open

All articles tagged with #jama network open

health21 hours ago•3 min saved

Large Review Links ADHD to Higher Mortality Risk, But Notes Medication May Offer Protection

A major meta-analysis published in JAMA Network Open indicates that individuals with ADHD face significantly higher risks of death from various causes, including suicide and injury. However, the study suggests that prescription medications for ADHD are associated with a lower risk of all-cause mortality. While the data confirms the dangers of untreated ADHD, it does not prove that medication directly causes the reduction in death rates.

via ScienceAlert|

#adhd #health #jama-network-open

health1 day ago•26 min saved

MRI Scans Reveal Silent Brain Damage in Healthy Adults Eating High Ultra-Processed Diets

A new Canadian study published in JAMA Network Open links high consumption of ultra-processed foods to silent brain damage in healthy adults aged 35 to 69. Using MRI scans on approximately 9,000 participants, researchers found that those with the highest intake were 40% more likely to show small areas of brain injury. These changes, which often lack obvious symptoms, may serve as early warning signs for future stroke or memory loss. The findings highlight a potential causal link between diet and neurological health, though the study’s cross-sectional design limits definitive conclusions.

via New York Post|

#brain-health #health #jama-network-open

health1 day ago•20 min saved

Psilocybin Shows Rapid Depression Relief, but Long-Term Gains Fade

A single dose of psilocybin rapidly reduced depression symptoms in a small Swedish trial, but the advantage over a placebo faded within a year.

via PsyPost|

#clinical-trial #depression #health

health10 days ago•4 min saved

Cannabis Use Linked to Hidden Sleep Disruption Over 35 Years

A 35-year study of 1,266 adults finds that both lifetime and recent cannabis use correlate with poorer objective sleep quality, including lower efficiency and higher fragmentation, in middle age. Despite these physiological disruptions, users did not report worse sleep on subjective surveys, indicating a disconnect between perceived and actual rest. The findings, published in JAMA Network Open, suggest cannabis may not be an effective long-term sleep aid.

via Neuroscience News|

#cannabis #cardia-study #health

health15 days ago•1 min saved

Gepotidacin Shows Rapid Symptom Relief for UTIs in New Trial

A new phase 3b study published in JAMA Network Open indicates that the oral antibiotic gepotidacin provides rapid symptom relief for uncomplicated urinary tract infections (UTIs), with over half of female patients experiencing improvement within 24 hours. The drug, approved by the FDA in 2025, offers a potential alternative for patients with recurrent UTIs and drug-resistant bacteria, though experts caution against overuse to prevent further resistance.

via medscape.com|

#antibiotic-resistance #gepotidacin #gsk

health16 days ago•26 min saved

Study Links Centenarian Parents to Longer, Healthier Lives for Offspring

A new study published in JAMA Network Open indicates that having a parent who lived past 100 is associated with significantly delayed mortality and lower risks of age-related diseases in their children. The research analyzed data from 4,030 participants across three major cohorts in the US and UK, finding that offspring of centenarians had reduced risks of cardiovascular disease, high blood pressure, and early death compared to those whose parents died by age 73. While only about 101,000 people in the US are centenarians, the findings suggest that genetic and environmental factors contributing to extreme longevity may be heritable, offering a model for identifying mechanisms that promote healthy aging.

via nypost.com|

#aging #centenarians #genetics

health-and-technology21 days ago•0 min saved

Study Links Early Smartphone Access to Higher Eating Disorder Rates in Teens

A new study published in JAMA Network Open finds that US children who own smartphones by age 12 are significantly more likely to develop eating disorder symptoms by age 14. The research, led by Dr. Jason Nagata of the University of California, San Francisco, analyzed data from the Adolescent Brain Cognitive Development Study. It highlights that early device access exposes preteens to appearance-focused content, which correlates with increased body dissatisfaction and disordered eating behaviors. Experts suggest delaying smartphone ownership by six months to a year may mitigate these risks.

via Futurism|

#adolescent-brain-cognitive-development-study #health-and-technology #jama-network-open

health23 days ago•14 min saved

Early Smartphone Access Linked to Higher Eating Disorder Risk in Teens

A new study published in JAMA Network Open finds that 12-year-olds with smartphones are significantly more likely to develop eating disorder symptoms by age 14. The research, led by Dr. Jason Nagata of UCSF, analyzed data from nearly 9,000 U.S. adolescents and highlights the risks of early exposure to appearance-focused content. Experts recommend delaying smartphone access and implementing strict usage guardrails to protect adolescent mental health during puberty.

via KSL News|

#adolescent-health #eating-disorders #health

health25 days ago•213 min saved

Study Links Early Smartphone Access to Higher Eating Disorder Risk in Teens

A new study published in JAMA Network Open finds that US adolescents who owned a smartphone at age 12 were significantly more likely to report eating disorder symptoms by age 14. The research, based on nearly 9,000 participants, highlights a correlation between early device access and disordered eating behaviors, though it does not prove causation. Experts advise parents to delay smartphone introduction and implement strict usage guardrails to protect children's mental health during puberty.

via CNN|

#child-development #eating-disorders #health

health1 month ago•21 min saved

Cefepime Linked to Small Rise in 30-Day Mortality in Large Meta-Analysis

A new meta-analysis of 110 randomized trials involving over 22,000 patients finds that the antibiotic cefepime is associated with a slightly higher risk of death within 30 days compared to other beta-lactam antibiotics. While the study does not recommend discontinuing the drug, it highlights potential risks related to dosing and neurotoxicity, particularly in adults with febrile neutropenia.

via New York Post|

#antibiotics #cefepime #febrile-neutropenia

health-and-science1 month ago•4 min saved

Centenarian Offspring Show 42% Lower Death Risk, Study Finds

A new study published in JAMA Network Open indicates that having a parent who lived to 100 is associated with significantly longer life and lower risks of heart disease and hypertension. Researchers analyzed data from three major cohorts, finding that centenarians’ offspring had a 42% lower risk of death, 33% lower risk of cardiovascular disease, and 32% lower risk of high blood pressure compared to controls. These benefits persisted even after adjusting for lifestyle factors, suggesting a genetic component to exceptional longevity. However, the study found no significant reduction in cancer risk, and stroke protection was inconsistent across cohorts. Experts note that while genetics play a major role, healthy behaviors remain essential for maximizing lifespan.

via The Washington Post|

#aging #cardiovascular-health #genetics

health1 month ago•1 min saved

New Analysis Links Common Hospital Antibiotic Cefepime to Higher Mortality Risk

A large meta-analysis published in JAMA Network Open suggests that cefepime, a widely used hospital antibiotic, may be associated with a higher risk of death compared to other beta-lactam antibiotics. The study, which reviewed 110 randomized clinical trials involving over 22,000 patients, found a 94.4% probability of increased all-cause mortality within 30 days of treatment. While the association was strongest in adults with febrile neutropenia, researchers emphasize that this does not prove causation. Experts suggest that dosing errors and neurotoxicity, rather than the drug itself, may drive the risk, urging better clinical guidance rather than discontinuation.

via FOX 13 Tampa Bay|

#antibiotics #cefepime #health

health1 month ago•1 min saved

Cefepime Linked to Higher Mortality in Global Antibiotic Review

A new global study published in JAMA Network Open finds that the antibiotic cefepime is associated with a higher risk of all-cause mortality compared to other beta-lactam antibiotics. The analysis reviewed 110 randomized trials involving over 22,000 patients, finding a 94.4% probability that cefepime leads to higher death rates. While the association is strongest in adults with febrile neutropenia, experts caution that the drug remains essential and that dosing errors, rather than the drug itself, may drive the risk.

via LiveNOW from FOX|

#antibiotics #cefepime #febrile-neutropenia

health1 month ago•4 min saved

Cefepime Linked to 94% Higher Death Risk in Major Antibiotic Review

A new meta-analysis of 110 trials involving 22,000 patients finds cefepime is associated with a 94.4% higher probability of 30-day all-cause mortality compared to other beta-lactam antibiotics, with the risk rising to 98.6% in peer-reviewed trials. Experts debate whether this reflects a drug safety issue or a dosing problem, noting that cefepime remains a first-line treatment for febrile neutropenia.

via Fox News|

#antibiotics #beta-lactams #cefepime

health-and-science1 month ago•3 min saved

Centenarian Offspring Show Significant Protection Against Cardiovascular Disease and Premature Death

A large-scale study confirms that children of centenarians have significantly lower risks of death, hypertension, and cardiovascular disease, suggesting a genetic component to exceptional longevity that persists even when lifestyle factors are controlled.

via ScienceAlert|

#cardiovascular-health #centenarians #genetics