Leucine Protects Mitochondrial Proteins to Boost Cellular Energy
Researchers at the University of Cologne have discovered that the amino acid leucine does more than build muscle; it actively regulates cellular energy production. By inhibiting the degradation of specific proteins on the outer membrane of mitochondria, leucine allows these organelles to function more efficiently. This mechanism, mediated by the quality control protein SEL1L, enables cells to adapt energy output to nutrient availability, with potential implications for cancer and metabolic disorders.