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Shmoose

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Mediterranean Diet Taps Tiny Mitochondrial Messengers for Heart and Brain Protection
health1 month ago

Mediterranean Diet Taps Tiny Mitochondrial Messengers for Heart and Brain Protection

An observational USC-led study found that older adults with strong adherence to a Mediterranean diet had higher blood levels of mitochondrial microproteins humanin and SHMOOSE, which are linked to cardiovascular and neuroprotective effects. Specific diet components correlated with each protein (olive oil, fish, and legumes with higher humanin; olive oil and lower refined carbs with higher SHMOOSE), suggesting a new pathway by which the diet may promote healthy aging and offering potential biomarkers for diet response, though causality cannot be established from the study.

Mediterranean Diet Reveals Hidden Cellular Anti-Aging Messengers
science3 months ago

Mediterranean Diet Reveals Hidden Cellular Anti-Aging Messengers

A USC-led study suggests that closer adherence to a Mediterranean-style diet raises mitochondrial microproteins humanin and SHMOOSE, which are linked to protection against aging-related diseases. The research found higher diet adherence correlated with increased levels of these proteins and lower oxidative stress, with olive oil, fish, and legumes connected to higher humanin and olive oil plus lower refined carbs linked to higher SHMOOSE. The work points to mitochondria-centered biomarkers and a potential precision-nutrition pathway, but is observational, so causality remains to be established.