Pilot Trial Finds 10-Minute Ultrasound Sessions Reduce Delusions in Schizophrenia
A small pilot study published in Nature found that a single 10-minute session of transcranial ultrasound stimulation (TUS) targeting the right globus pallidus interna (GPi) significantly reduced delusion severity in patients with schizophrenia. While the treatment was safe and well-tolerated, researchers emphasize that larger trials are needed to confirm efficacy, as the current study involved only 10 participants and lacked neuroimaging confirmation of target engagement.