All articles tagged with #treatment resistant
A publicly funded randomized trial found that a 25mg dose of psilocybin plus psychological support significantly boosted response (43% at 3 weeks, 56% at 6 weeks) and remission (40% at 3 weeks vs 3% placebo), with effects sustained through six weeks, suggesting psilocybin therapy could help treatment-resistant depression and warrants larger, publicly funded trials in community settings.
Matt Baszucki, diagnosed with treatment-resistant bipolar disorder, found relief through a ketogenic diet suggested by Dr. Christopher Palmer at Harvard Medical School after years of struggling with medication and hospitalizations. The diet, combined with exercise and medication, helped stabilize his mood and reduce his symptoms, allowing him to lead a more normal life. While the approach is unconventional and not without risks, it has shown promising results in managing severe mental illness.
The first outbreak of the treatment-resistant C. auris fungus has been confirmed in Seattle, with four patients linked to Kindred Hospital on First Hill testing positive for the fungus, which can cause serious infections and is resistant to treatment medications. Health officials are emphasizing the importance of early identification and proactive screening to control the spread of C. auris in healthcare facilities.
Deep brain stimulation (DBS) may be a beneficial treatment for individuals with treatment-resistant alcohol use disorder, according to a study published in Translational Psychiatry. While the study did not show significant results in terms of continuous abstinence, it indicated that DBS might help reduce symptoms associated with alcohol use disorder, such as reducing cravings and increasing periods of abstinence. DBS involves implanting a device in the brain to deliver electrical impulses to specific regions. The study was a double-blind, randomized controlled trial involving 12 participants, and while it did not find a statistically significant difference between the active DBS and placebo groups in terms of abstinence, it did show a medium effect of DBS in treating alcohol use disorder. Further research with larger sample sizes is needed to confirm these findings.
Two patients in New York City have been diagnosed with treatment-resistant Tinea indotineae, a highly contagious and widespread form of ringworm that does not respond to standard antifungal medications. This marks the first time the infection has been reported in the United States. Health care providers should consider Tinea indotineae as a diagnosis when first-line medications and antifungal agents do not relieve symptoms, and any provider who suspects this infection should contact public health officials. People who suspect they may have this infection should see their doctor or a dermatologist.