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Bipolar Disorder

All articles tagged with #bipolar disorder

Ozempic Shows Promise for Mood Stability in Bipolar Disorder
health8 hours ago

Ozempic Shows Promise for Mood Stability in Bipolar Disorder

Australian researchers analyzed 15,000 people over 15 years and found that semaglutide (Ozempic) lowered the risk of psychiatric hospitalization in bipolar disorder by about 21%, a benefit not seen with related GLP-1 drugs. The findings suggest GLP-1 signaling may protect the brain by reducing inflammation and cellular stress, potentially improving mood stability, though more research is needed to confirm direct effects on bipolar symptoms.

via New York Post|
#bipolar-disorder#glp-1#health
Common Brain Network Disruptions Link Schizophrenia and Bipolar Disorder
science5 days ago

Common Brain Network Disruptions Link Schizophrenia and Bipolar Disorder

A study in Frontiers in Psychiatry compared resting-state fMRI from 89 people with schizophrenia, 57 with bipolar I disorder, and 45 healthy controls, finding reduced coordination among distant brain regions in both patient groups—more widespread changes in schizophrenia. This suggests overlapping patterns of brain-network disruption between the two conditions, though not a single wiring fault; results cannot diagnose individuals yet and highlight the need for larger, longitudinal research.

via Yahoo|
#bipolar-disorder#brain-imaging#mental-health
Lindsay Clancy trial nears defense rest as mental-health testimony dominates Day 18
usnews5 days ago

Lindsay Clancy trial nears defense rest as mental-health testimony dominates Day 18

Day 18 of the Lindsay Clancy murder trial focused on potential defense rest as forensic psychiatrist Dr. Phillip Resnick testified via Zoom about Clancy's bipolar II disorder with severe depression and postpartum psychosis; prosecutors say she killed her three children, while the defense argues mental illness excuses liability. Technical Zoom issues caused breaks, and closing arguments could begin next week if the defense rests as expected.

via NBC Boston|
#bipolar-disorder#dr-phillip-resnick#lindsay-clancy
Clancy Trial Day 17: Jury Excused After One Witness, Closings Loom
crime6 days ago

Clancy Trial Day 17: Jury Excused After One Witness, Closings Loom

On Day 17 of the Lindsay Clancy murder trial in Massachusetts, the jury was dismissed early after just one witness—Sheila Cavanaugh, a hospital chaplain—testified. Prosecutors say Clancy killed her three children and then jumped from a second‑story window, while the defense argues bipolar disorder and postpartum psychosis mitigate responsibility. The day included discussions over possible jury instructions regarding intoxication, and closings are expected Monday or Tuesday with further testimony planned for Friday.

via NBC Boston|
#bipolar-disorder#crime#lindsay-clancy
Family fears release of NC street attacker after string of terrifying encounters
us-news17 days ago

Family fears release of NC street attacker after string of terrifying encounters

Di-Quan Schafar Hunt, a 32-year-old North Carolina man with a lengthy criminal history, was arrested after livestreaming and attacking women in Charlotte. His sister and family say he has shown violent behavior toward neighbors and relatives, and experts believe he has PTSD and bipolar disorder but refuses treatment. The family fears his release without proper care, as authorities plan to charge him with assault with a deadly weapon upon release from a medical facility.

via New York Post|
#arrests#assault#bipolar-disorder
Shia LaBeouf's On-Set Breakdowns Highlight 'Maximum Empathy' for The Rooster Prince
entertainment1 month ago

Shia LaBeouf's On-Set Breakdowns Highlight 'Maximum Empathy' for The Rooster Prince

Writer-director Josh Soskin recalls Shia LaBeouf’s explosive, deeply painful on-set performance for The Rooster Prince, a film inspired by his brother’s bipolar disorder; a self-tape moment—“maximum empathy”—helps Soskin rally the crew and frame the production as a raw exploration of mental illness in art, even as LaBeouf later faces legal troubles.

via Variety|
#bipolar-disorder#empathy#entertainment
Genetic Overlap Across Psychiatric Disorders Reshapes Mental Illness Diagnosis
science1 month ago

Genetic Overlap Across Psychiatric Disorders Reshapes Mental Illness Diagnosis

Large-scale analyses of over 1 million people across 14 psychiatric conditions identify five shared genetic signatures that drive most risk, with schizophrenia and bipolar disorder sharing about 70% of their genetic signal. The findings suggest common biological pathways across disorders, challenging traditional separate diagnoses and hinting at unified treatments targeting pleiotropic genetic factors.

via ScienceAlert|
#bipolar-disorder#genetics#pleiotropy
Creatine Shows Mood-Boosting Hints in Depression, but Big Caveats Remain
health1 month ago

Creatine Shows Mood-Boosting Hints in Depression, but Big Caveats Remain

A Brain Medicine review of six randomized trials (238 participants) finds mixed evidence that creatine, a brain-energy booster, can help depression: some small studies show benefit in women with major depressive disorder when added to escitalopram or CBT, others show no effect, and a bipolar-depression trial raised safety concerns about mood switching. The studies are small and heterogeneous, so researchers urge larger, longer trials across diverse groups and testing creatine with established treatments; creatine is not yet a proven depression treatment.

via ZME Science|
#bipolar-disorder#clinical-trials#creatine
Low-dose lithium explored as potential disease-modifying therapy for Alzheimer's
science2 months ago

Low-dose lithium explored as potential disease-modifying therapy for Alzheimer's

New research argues that low-dose lithium, a long-used bipolar disorder drug, may slow Alzheimer's progression by boosting brain resilience and countering neuroprogression, acting on multiple pathways (BDNF, bcl-2, GSK-3) to promote neuroprotection. While traditional psychiatric doses carry risks to kidney and thyroid function, the study suggests much lower doses could offer benefits with fewer side effects, and experts emphasize that rigorous clinical trials are needed before any change in medical practice. The findings fuel interest in repurposing an affordable, widely available drug as part of a multi-target approach to dementia, but caution remains about safety and efficacy in older adults.

via Medical News Today|
#alzheimers-disease#bipolar-disorder#lithium