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Vaccine Effectiveness

All articles tagged with #vaccine effectiveness

CDC Acting Director Delayed Vaccine-Effectiveness Paper Over Methodology Concerns
health4 hours ago

CDC Acting Director Delayed Vaccine-Effectiveness Paper Over Methodology Concerns

The CDC’s acting director, Dr. Jay Bhattacharya, reportedly delayed the release of an MMWR study showing Covid vaccines reduce severe illness, citing concerns about the observational method; the paper, based on a test‑negative design, was expected to indicate about a 50% reduction in severe outcomes among adults with the 2025‑26 vaccine formulation. Officials say leadership routinely reviews papers for methodological issues, while critics within and around the Trump administration have framed vaccine research debates as political interference. If the MMWR paper isn’t published, the authors could submit the findings to a medical journal after further analysis.

CDC delays key COVID vaccine-benefits report, prompting questions about its methods
health2 days ago

CDC delays key COVID vaccine-benefits report, prompting questions about its methods

The acting CDC director delayed publication of a report showing the COVID-19 vaccine reduced emergency department visits and hospitalizations for healthy adults last winter by about half, citing concerns with the methodology. The move, while the design has long been used to test vaccine effectiveness, has drawn criticism that vaccine benefits may be downplayed and was reported by scientists who spoke on condition of anonymity.

US flu vaccine underperforms against new strain, officials say
health28 days ago

US flu vaccine underperforms against new strain, officials say

CDC data show this season’s flu vaccine was about 25%–30% effective at preventing illness requiring medical care for adults and roughly 40% for vaccinated children, due mainly to a newly dominant H3N2 subclade not well matched by the vaccine. An estimated 27 million illnesses, 350,000 hospitalizations and 22,000 deaths have occurred; adult vaccination is about 46.5% and around 48% of kids have been vaccinated. Vaccination remains worthwhile to reduce severe illness, and next season’s vaccines will be updated to address the subclade.

"Anticipating the Future of the Coronavirus"
health2 years ago

"Anticipating the Future of the Coronavirus"

Scientists are closely monitoring the continuing evolution of the coronavirus and the body's immune responses in order to anticipate and prevent a potential resurgence, as well as to gain a better understanding of long Covid. Research efforts include studying how the virus behaves and evolves as populations build immunity, investigating the body's response to the infection, and estimating vaccine effectiveness in the midst of evolving respiratory conditions.

"Updated COVID-19 Vaccine Dose Recommended for Seniors by CDC"
health2 years ago

"Updated COVID-19 Vaccine Dose Recommended for Seniors by CDC"

The CDC is recommending that adults aged 65 and older receive an additional dose of the updated 2023-2024 COVID-19 vaccine to address the increased risk of severe disease in this age group. This recommendation follows previous guidance for immunocompromised individuals and aims to restore waning protection and provide increased protection for older adults, who are disproportionately impacted by COVID-19. The CDC emphasizes the importance of vaccination for this age group and continues to monitor vaccine safety and effectiveness.

"2023-24 Flu Vaccine Shows 42% Effectiveness, in Line with Past Years: CDC Report"
health2 years ago

"2023-24 Flu Vaccine Shows 42% Effectiveness, in Line with Past Years: CDC Report"

The CDC has reported that this season's flu vaccines have been 42% effective, offering better protection than in some recent years. The vaccines were found to be between 52% and 61% effective in children and 41% to 44% effective in adults. However, declining vaccination rates could still lead to fewer hospitalizations and deaths prevented by vaccines. The effectiveness against influenza B infections was notably high, with the CDC recommending people to get vaccinated as significant flu activity can last until May. Additionally, the FDA is set to vote on a major change to next season's influenza vaccines, potentially transitioning from quadrivalent to trivalent formulations.

"Health Officials Recommend Second COVID-19 Shot for Older Adults"
health2 years ago

"Health Officials Recommend Second COVID-19 Shot for Older Adults"

The CDC recommended that people 65 and older receive a second dose of a coronavirus vaccine due to their higher risk for severe illness. The recommendation aims to provide added protection, especially as hospitalization rates for older adults remain high. While there are concerns about potential drawbacks, such as decreased public confidence and vaccine fatigue, the CDC emphasizes that updated vaccines continue to be effective against different circulating variants.

"Assessing the Effectiveness of Flu Vaccines in the US: New Data and Insights"
health2 years ago

"Assessing the Effectiveness of Flu Vaccines in the US: New Data and Insights"

Early estimates indicate that flu shots in the US are around 40% effective in preventing adults from severe flu illness, with children being roughly 60% less likely to require treatment. Annual flu vaccines are recommended for everyone 6 months and older, and about half of eligible kids and adults received flu shots in the last several months. The effectiveness of the shots is influenced by the match against circulating flu strains, and some concerns have been raised about potential diminishing returns for annual influenza immunization.

"Maximizing COVID-19 Vaccine Effectiveness: The Impact of Alternating Arms"
health2 years ago

"Maximizing COVID-19 Vaccine Effectiveness: The Impact of Alternating Arms"

A study from Oregon Health and Science University suggests that receiving COVID-19 vaccine doses in different arms may lead to a substantially stronger immune response compared to receiving both doses in the same arm. The research found that participants who received "contralateral" shots in different arms had a significantly increased antibody response, which continued to grow over time and was even more effective against the Omicron variant. While more research is needed, the findings may have implications for other multidose vaccinations, potentially impacting how vaccines are administered in the future.

"Comparing COVID-19 Vaccine Effectiveness: Latest Findings and Recommendations"
health2 years ago

"Comparing COVID-19 Vaccine Effectiveness: Latest Findings and Recommendations"

University of Michigan researchers analyzed over 80 studies and 150 million patient observations to assess the effectiveness of COVID-19 vaccine doses beyond the primary series, finding significant benefits of monovalent and bivalent boosters in preventing hospitalization and death. Their study supports the periodic update of vaccines to match circulating virus variants and emphasizes the importance of robust and reproducible results to solidify public trust and fight misinformation. The research, published in Science Advances, highlights the potential of biostatistics and epidemiology in evaluating vaccine effectiveness and underscores the strong protection provided by COVID-19 vaccines against severe illness and hospitalization.

"Updated COVID-19 Vaccine Provides 54% Protection Against Symptomatic Cases, CDC Reports"
health2 years ago

"Updated COVID-19 Vaccine Provides 54% Protection Against Symptomatic Cases, CDC Reports"

The CDC's recent study found that the updated COVID-19 vaccine is 54% effective against symptomatic infection in adults, offering increased protection against recent variants of the virus. The study, based on observations of 9,000 people from mid-September 2023 to January 2024, showed that the new shots provide defense against JN.1 and other circulating lineages. However, the results are not yet conclusive, and further studies will assess the vaccine's effectiveness in preventing severe symptoms and hospitalizations. The CDC urges everyone over 6 months to get the new shots for protection against COVID and evolving variants, as updated vaccination coverage in the U.S. remains low.

"Latest COVID-19 Vaccine Shows Strong Protection Against Severe Disease and Symptomatic Infection"
health2 years ago

"Latest COVID-19 Vaccine Shows Strong Protection Against Severe Disease and Symptomatic Infection"

University of Michigan researchers evaluated 80 studies and 150 million patient observations to understand the effectiveness of COVID-19 vaccine doses, finding that all sequential doses provided substantial benefit in preventing hospitalization and death. They observed stronger estimates for the fall 2022 omicron-specific vaccine dose and support the practice of periodically updating COVID-19 vaccines for currently circulating variants. The study's findings suggest the utility of updating vaccines and establish an analytic pipeline for studying the effectiveness of future annual vaccine formulations.