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Virus Reactivation

All articles tagged with #virus reactivation

health2 months ago•3 min saved

Dormant viruses wake in severe COVID-19 patients, new study suggests

A large multi-center study of 1,154 hospitalized COVID-19 patients found 11 dormant viruses reactivated within 40 days of admission, including Epstein-Barr, cytomegalovirus, herpes simplex virus-1 and Anelloviridae; Anelloviridae reactivation was linked to long COVID and disability, while EBV/CMV reactivation appeared tied to inflammation rather than immune suppression. The study does not prove causation but may help explain long COVID and guide future diagnostics and therapies, though results apply to severe cases only.

via ABC News - Breaking News, Latest News and Videos|

#anelloviridae #covid-19 #health

science2 months ago•6 min saved

Severe COVID-19 May Trigger Dormant Viruses, Tied to Long COVID

A Nature study of more than 1,000 hospitalized COVID-19 patients finds that severe infection can wake up dormant viruses—including Epstein–Barr virus and anelloviruses—linked to the development of long COVID, with different viral families reactivating at separate times and immune stress likely driving the process.

via Nature|

#anelloviruses #covid-19 #epstein-barr-virus

science2 months ago•89 min saved

Chronic Virus Reactivation Linked to Severity and Long COVID in COVID-19 Patients

A large, longitudinal study of 1,154 hospitalized COVID-19 patients using multi-omic analyses found significant reactivation of chronic viruses, especially Herpesviridae (EBV, CMV, HSV) and Anelloviridae, during acute illness with distinct timing for different viruses. Reactivation correlated with greater disease severity and adverse outcomes and persisted into convalescence, with Anelloviridae associated with long COVID. Although causality isn’t established, the results show frequent viral reactivation in immunocompetent patients during severe illness and reveal immune, transcriptomic, and metabolic changes linked to reactivation, offering potential prognostic and therapeutic insights for acute COVID-19 and long COVID.

via Nature|

#anelloviridae #herpesviridae #long-covid