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Vmpfc

All articles tagged with #vmpfc

science1 month ago•6 min saved

Timing of Childhood Trauma Rewires Brain–Immune Fear Circuits

A 128-participant fMRI study from Guangzhou University links the type and timing of childhood maltreatment to lasting neuro-immune changes: early childhood abuse (ages 1–11) modulates amygdala–IL-8 coupling during fear learning, late adolescence neglect (ages 12–18) reshapes vmPFC–IL-8 connections, and early neglect alters amygdala–vmPFC and hippocampus–vmPFC connectivity with IL-17; the findings support a maturation-matched vulnerability and point to therapies that target both fear circuits and systemic inflammation.

via Neuroscience News|

#amygdala #childhood-trauma #fear-learning

science4 months ago•8 min saved

The Brain's Emotional GPS: Mapping Feelings Across Valence and Arousal

New research shows the hippocampus and ventromedial prefrontal cortex create a map-like representation of emotions in a two-dimensional valence–arousal space. The interior hippocampus stores broad emotion categories, the posterior hippocampus handles finer distinctions, and the vmPFC tracks relationships between them. Using fMRI, pattern recognition, and the Tolman–Eichenbaum Machine AI model with the Emo-FiLM film dataset, researchers replicated brain patterns and highlighted how greater emotional granularity correlates with better mental health, suggesting affect labeling could help expand the emotional map and aid in treating depression and anxiety.

via Neuroscience News|

#depression-anxiety #emotional-granularity #emotional-map

science2 years ago•3 min saved

"Key Brain Region Identified for Altruistic Behavior"

Researchers from the University of Birmingham and the University of Oxford have identified the ventromedial prefrontal cortex (vmPFC) as crucial for prosocial behaviors, such as helping others. The study, involving patients with brain damage, revealed that damage to the vmPFC significantly reduces the willingness to exert effort to help others. This discovery could inform new treatments for social interaction disorders and enhance understanding of how to motivate people to address global challenges.

via Medical Xpress|

#brain #brain-damage #motivation