Aging Muscle Stem Cells: Speedy Repair Comes at a Survival Cost

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Source: ScienceDaily
Aging Muscle Stem Cells: Speedy Repair Comes at a Survival Cost
Photo: ScienceDaily
TL;DR

UCLA researchers found aging muscle stem cells accumulate the protein NDRG1, which slows repair by dampening mTOR signaling, but blocking NDRG1 reactivates youthful repair in old cells at the expense of long‑term survival, highlighting a trade‑off between rapid healing and stem cell longevity.

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