Microglial switch may decide Alzheimer's dementia risk
TL;DR Summary
A human-donor study links a pivotal shift in brain microglia—the immune cells that respond to amyloid plaques and tau—to whether Alzheimer's pathology progresses to dementia, suggesting therapies that preserve beneficial microglial states and target their transition timing.
Topics:health#alzheimers-disease#amyloid-b-plaques#dementia#health-and-medicine#microglia#tau-pathology
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