Shingrix May Cut Dementia Risk by Nearly a Quarter in Seniors
TL;DR
A Brown University–led analysis of more than 500,000 adults aged 66+ in skilled nursing facilities found that receiving at least one Shingrix dose was associated with a 24% lower risk of a dementia diagnosis over four years, compared with unvaccinated peers (18.8% vs 24.6%). Using Medicare claims and electronic health records with target trial emulation, the study cannot prove causation and may reflect healthier baseline status among vaccine recipients; more research, including trials, is needed. Funding from GlaxoSmithKline was disclosed, though the sponsor had no control over study design or publication.
Topics:healthhealth-and-medicine#aging#dementia-risk#health-and-medicine#medicare-data#shingles-vaccine#vaccines
- Shingles vaccine linked to 24% lower dementia risk Science Daily
- The dementia vaccine some of us are taking without realising BBC Science Focus Magazine
- Shingles vaccine may help lower risk of dementia Leader Publications
- Shingles Shot May Help Protect the Brain Royal Examiner
- A natural experiment involving more than 280,000 Welsh adults found that shingles vaccination cut new dementia diagnoses by 20% over seven years. Months later, the same researchers found something even stranger: the apparent benefit extended to peopl ScienceBlog.com
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